Tanneberger, K., Otto, C., & Schirmer, K. (2010). Assessment of chemicals: fish cells as an alternative to whole fish. Eawag News [engl. ed.], 68, 25-27.
Every year, hundreds of thousands of fish die in toxicology tests worldwide. Among the possible alternatives being explored by Eawag, fish cells are particularly promising. However, the toxic effects of chemicals are generally less marked in fish cells than in whole fish. Here, we explain the reasons for this - and discuss how fish cell-based assays can be optimized.