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Impact of wastewater on the microbial diversity of periphyton and its tolerance to micropollutants in an engineered flow-through channel system
Carles, L., Wullschleger, S., Joss, A., Eggen, R. I. L., Schirmer, K., Schuwirth, N., … Tlili, A. (2021). Impact of wastewater on the microbial diversity of periphyton and its tolerance to micropollutants in an engineered flow-through channel system. Water Research, 203, 117486 (14 pp.). https://doi.org/10.1016/j.watres.2021.117486
Toxicity and translocation of Ag, CuO, ZnO and TiO<sub>2</sub> nanoparticles upon exposure to fish intestinal epithelial cells
Geppert, M., Sigg, L., & Schirmer, K. (2021). Toxicity and translocation of Ag, CuO, ZnO and TiO2 nanoparticles upon exposure to fish intestinal epithelial cells. Environmental Science: Nano, 8(8), 2249 (12 pp.). https://doi.org/10.1039/D1EN00050K
Zebrafish early life stages as alternative model to study 'designer drugs': concordance with mammals in response to opioids
Kirla, K. T., Erhart, C., Groh, K. J., Stadnicka-Michalak, J., Eggen, R. I. L., Schirmer, K., & Kraemer, T. (2021). Zebrafish early life stages as alternative model to study 'designer drugs': concordance with mammals in response to opioids. Toxicology and Applied Pharmacology, 419, 115483 (11 pp.). https://doi.org/10.1016/j.taap.2021.115483
<em>In vitro</em> digestion of tire particles in a fish model (<em>Oncorhynchus mykiss</em>): solubilization kinetics of heavy metals and effects of food coingestion
Masset, T., Ferrari, B. J. D., Oldham, D., Dudefoi, W., Minghetti, M., Schirmer, K., … Breider, F. (2021). In vitro digestion of tire particles in a fish model (Oncorhynchus mykiss): solubilization kinetics of heavy metals and effects of food coingestion. Environmental Science and Technology, 55(23), 15788-15796. https://doi.org/10.1021/acs.est.1c04385
Cytotoxicity, accumulation and translocation of silver and silver sulfide nanoparticles in contact with rainbow trout intestinal cells
Opršal, J., Knotek, P., Zickler, G. A., Sigg, L., Schirmer, K., Pouzar, M., & Geppert, M. (2021). Cytotoxicity, accumulation and translocation of silver and silver sulfide nanoparticles in contact with rainbow trout intestinal cells. Aquatic Toxicology, 237, 105869 (11 pp.). https://doi.org/10.1016/j.aquatox.2021.105869
Limitations and uncertainties of acute fish toxicity assessments can be reduced using alternative methods
Paparella, M., Scholz, S., Belanger, S., Braunbeck, T., Bicherel, P., Connors, K., … Walter-Rohde, S. (2021). Limitations and uncertainties of acute fish toxicity assessments can be reduced using alternative methods. ALTEX: Alternatives to Animal Experimentation, 38(1), 20-32. https://doi.org/10.14573/altex.2006051
New stable cell lines derived from the proximal and distal intestine of rainbow trout (<em>Oncorhynchus mykiss</em>) retain several properties observed in vivo
Pasquariello, R., Verdile, N., Pavlovic, R., Panseri, S., Schirmer, K., Brevini, T. A. L., & Gandolfi, F. (2021). New stable cell lines derived from the proximal and distal intestine of rainbow trout (Oncorhynchus mykiss) retain several properties observed in vivo. Cells, 10(6), 1555 (17 pp.). https://doi.org/10.3390/cells10061555
Validation report for the test guideline 249 on fish cell line acute toxicity - the RTgill-W1 cell line assay
Schirmer, K., Fischer, M., Eszter, S., Andersen, S., Kunz, P., & Lillicrap, A. (2021). Validation report for the test guideline 249 on fish cell line acute toxicity - the RTgill-W1 cell line assay. (Series on testing and assessment, Report No.: 334). OECD. https://doi.org/10.1787/c66d5190-en
Predicting exposure concentrations of chemicals with a wide range of volatility and hydrophobicity in different multi-well plate set-ups
Stadnicka-Michalak, J., Bramaz, N., Schönenberger, R., & Schirmer, K. (2021). Predicting exposure concentrations of chemicals with a wide range of volatility and hydrophobicity in different multi-well plate set-ups. Scientific Reports, 11, 4860 (14 pp.). https://doi.org/10.1038/s41598-021-84109-9
Characterization of the ERK1/2 phosphorylation profile in human and fish liver cells upon exposure to chemicals of environmental concern
Stanic, B., Petrovic, J., Basica, B., Kaisarevic, S., Schirmer, K., & Andric, N. (2021). Characterization of the ERK1/2 phosphorylation profile in human and fish liver cells upon exposure to chemicals of environmental concern. Environmental Toxicology and Pharmacology, 88, 103749 (9 pp.). https://doi.org/10.1016/j.etap.2021.103749
Toxic effects of substituted <em>p</em>-benzoquinones and hydroquinones in <em>in vitro</em> bioassays are altered by reactions with the cell assay medium
Tentscher, P. R., Escher, B. I., Schlichting, R., König, M., Bramaz, N., Schirmer, K., & von Gunten, U. (2021). Toxic effects of substituted p-benzoquinones and hydroquinones in in vitro bioassays are altered by reactions with the cell assay medium. Water Research, 202, 117415 (12 pp.). https://doi.org/10.1016/j.watres.2021.117415
A ribonucleoprotein transfection strategy for CRISPR/Cas9‐mediated gene editing and single cell cloning in rainbow trout cells
Zoppo, M., Okoniewski, N., Pantelyushin, S., vom Berg, J., & Schirmer, K. (2021). A ribonucleoprotein transfection strategy for CRISPR/Cas9‐mediated gene editing and single cell cloning in rainbow trout cells. Cell and Bioscience, 11(1), 103 (15 pp.). https://doi.org/10.1186/s13578-021-00618-0
Common gene expression patterns in environmental model organisms exposed to engineered nanomaterials: a meta-analysis
Burkard, M., Betz, A., Schirmer, K., & Zupanic, A. (2020). Common gene expression patterns in environmental model organisms exposed to engineered nanomaterials: a meta-analysis. Environmental Science and Technology, 54(1), 335-344. https://doi.org/10.1021/acs.est.9b05170
Extending the concept of predicting fish acute toxicity <em>in vitro</em> to the intestinal cell line RTgutGC
Schug, H., Maner, J., Hülskamp, M., Begnaud, F., Debonneville, C., Berthaud, F., … Schirmer, K. (2020). Extending the concept of predicting fish acute toxicity in vitro to the intestinal cell line RTgutGC. ALTEX: Alternatives to Animal Experimentation, 37(1), 37-46. https://doi.org/10.14573/altex.1905032
Biotransformation capacity of zebrafish (&lt;em&gt;Danio rerio&lt;/em&gt;) early life stages: functionality of the mercapturic acid pathway
Tierbach, A., Groh, K. J., Schoenenberger, R., Schirmer, K., & Suter, M. J. F. (2020). Biotransformation capacity of zebrafish (Danio rerio) early life stages: functionality of the mercapturic acid pathway. Toxicological Sciences, 176(2), 355-365. https://doi.org/10.1093/toxsci/kfaa073
Characterization of the mercapturic acid pathway, an important phase II biotransformation route, in a zebrafish embryo cell line
Tierbach, A., Groh, K. J., Schoenenberger, R., Schirmer, K., & Suter, M. J. F. (2020). Characterization of the mercapturic acid pathway, an important phase II biotransformation route, in a zebrafish embryo cell line. Chemical Research in Toxicology, 33(11), 2863-2871. https://doi.org/10.1021/acs.chemrestox.0c00315
LC-APCI(-)-MS determination of 1-chloro-2,4-dinitrobenzene, a model substrate for glutathione S-transferases
Tierbach, A., Groh, K. J., Schönenberger, R., Schirmer, K., & Suter, M. J. F. (2020). LC-APCI(-)-MS determination of 1-chloro-2,4-dinitrobenzene, a model substrate for glutathione S-transferases. Journal of the American Society for Mass Spectrometry, 31, 467-472. https://doi.org/10.1021/jasms.9b00116
Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor)
Burkard, M., Bengtson Nash, S., Gambaro, G., Whitworth, D., & Schirmer, K. (2019). Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor). Cell Biology and Toxicology, 35(4), 387-398. https://doi.org/10.1007/s10565-018-09457-1
Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (<i>Oncorhynchus mykiss</i>)
Bussolaro, D., Wright, S. L., Schnell, S., Schirmer, K., Bury, N. R., & Arlt, V. M. (2019). Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (Oncorhynchus mykiss). Environmental Pollution, 248, 706-714. https://doi.org/10.1016/j.envpol.2019.02.066
Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine &lt;em&gt;in vitro&lt;/em&gt;
Drieschner, C., Könemann, S., Renaud, P., & Schirmer, K. (2019). Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro. Lab on a Chip, 19(19), 3268-3276. https://doi.org/10.1039/C9LC00415G
 

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