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Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor)
Burkard, M., Bengtson Nash, S., Gambaro, G., Whitworth, D., & Schirmer, K. (2019). Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor). Cell Biology and Toxicology, 35(4), 387-398. https://doi.org/10.1007/s10565-018-09457-1
Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (<i>Oncorhynchus mykiss</i>)
Bussolaro, D., Wright, S. L., Schnell, S., Schirmer, K., Bury, N. R., & Arlt, V. M. (2019). Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (Oncorhynchus mykiss). Environmental Pollution, 248, 706-714. https://doi.org/10.1016/j.envpol.2019.02.066
Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine &lt;em&gt;in vitro&lt;/em&gt;
Drieschner, C., Könemann, S., Renaud, P., & Schirmer, K. (2019). Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro. Lab on a Chip, 19(19), 3268-3276. https://doi.org/10.1039/C9LC00415G
Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF
Drieschner, C., Vo, N. T. K., Schug, H., Burkard, M., Bols, N. C., Renaud, P., & Schirmer, K. (2019). Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF. Cytotechnology, 71(4), 835-848. https://doi.org/10.1007/s10616-019-00327-0
Repeatability and reproducibility of the RTgill-W1 cell line assay for predicting fish acute toxicity
Fischer, M., Belanger, S. E., Berckmans, P., Bernhard, M. J., Bláha, L., Coman Schmid, D. E., … Schirmer, K. (2019). Repeatability and reproducibility of the RTgill-W1 cell line assay for predicting fish acute toxicity. Toxicological Sciences, 169(2), 353-364. https://doi.org/10.1093/toxsci/kfz057
Interference of silver nanoparticles with essential metal homeostasis in a novel enterohepatic fish &lt;em&gt;in vitro&lt;/em&gt; system
Minghetti, M., & Schirmer, K. (2019). Interference of silver nanoparticles with essential metal homeostasis in a novel enterohepatic fish in vitro system. Environmental Science: Nano, (6), 1777-1790. https://doi.org/10.1039/C9EN00310J
Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. &lt;em&gt;Environmental Pollution&lt;/em&gt; 252
Schirmer, K., Stadnicka-Michalak, J., Belanger, S. E., Blaha, L., Bols, N. C., Dyer, S. D., … Zupanic, A. (2019). Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476–482. Environmental Pollution, 254(B), 113060 (3 pp.). https://doi.org/10.1016/j.envpol.2019.113060
Extending the concept of predicting fish acute toxicity &lt;em&gt;in vitro&lt;/em&gt; to the intestinal cell line RTgutGC
Schug, H., Maner, J., Hülskamp, M., Begnaud, F., Debonneville, C., Berthaud, F., … Schirmer, K. (2019). Extending the concept of predicting fish acute toxicity in vitro to the intestinal cell line RTgutGC. ALTEX: Alternatives to Animal Experimentation, (9 pp.). https://doi.org/10.14573/altex.1905032
Intestinal fish cell barrier model to assess transfer of organic chemicals in vitro: an experimental and computational study
Schug, H., Maner, J., Begnaud, F., Berthaud, F., Gimeno, S., Schirmer, K., & Županič, A. (2019). Intestinal fish cell barrier model to assess transfer of organic chemicals in vitro: an experimental and computational study. Environmental Science and Technology, 53(20), 12062-12070. https://doi.org/10.1021/acs.est.9b04281
Time- and concentration-dependent expression of immune and barrier genes in the RTgutGC fish intestinal model following immune stimulation
Schug, H., Yue, Y., Krese, R., Fischer, S., Kortner, T. M., & Schirmer, K. (2019). Time- and concentration-dependent expression of immune and barrier genes in the RTgutGC fish intestinal model following immune stimulation. Fish and Shellfish Immunology, 88, 308-317. https://doi.org/10.1016/j.fsi.2019.02.036
In vitro-in vivo extrapolation to predict bioaccumulation and toxicity of chemicals in fish using physiologically based toxicokinetic models
Stadnicka-Michalak, J., & Schirmer, K. (2019). In vitro-in vivo extrapolation to predict bioaccumulation and toxicity of chemicals in fish using physiologically based toxicokinetic models. Methods in pharmacology and toxicology. . https://doi.org/10.1007/7653_2019_34
Evaluating environmental risk assessment models for nanomaterials according to requirements along the product innovation Stage-Gate process
Sørensen, S. N., Baun, A., Burkard, M., Dal Maso, M., Foss Hansen, S., Harrison, S., … Spurgeon, D. J. (2019). Evaluating environmental risk assessment models for nanomaterials according to requirements along the product innovation Stage-Gate process. Environmental Science: Nano, 6, 505-518. https://doi.org/10.1039/C8EN00933C
Imidacloprid induces adverse effects on fish early life stages that are more severe in Japanese medaka (&lt;em&gt;Oryzias latipes&lt;/em&gt;) than in zebrafish (&lt;em&gt;Danio rerio&lt;/em&gt;)
Vignet, C., Cappello, T., Fu, Q., Lajoie, K., De Marco, G., Clérandeau, C., … Cachot, J. (2019). Imidacloprid induces adverse effects on fish early life stages that are more severe in Japanese medaka (Oryzias latipes) than in zebrafish (Danio rerio). Chemosphere, 225, 470-478. https://doi.org/10.1016/j.chemosphere.2019.03.002
Rainbow trout (<i>Oncorhynchus mykiss</i>) intestinal epithelial cells as a model for studying gut immune function and effects of functional feed ingredients
Wang, J., Lei, P., Gamil, A. A. A., Lagos, L., Yue, Y., Schirmer, K., … Kortner, T. M. (2019). Rainbow trout (Oncorhynchus mykiss) intestinal epithelial cells as a model for studying gut immune function and effects of functional feed ingredients. Frontiers in Immunology, 10, 152 (17 pp.). https://doi.org/10.3389/fimmu.2019.00152
What is the role of fish intestine as environment-organism barrier? Mechanistic investigations using fish intestinal cells on a chip
Drieschner, C. (2018). What is the role of fish intestine as environment-organism barrier? Mechanistic investigations using fish intestinal cells on a chip (Doctoral dissertation). EPFL Lausanne, Lausanne, Switzerland, 102 p.
Long-term exposure to silver nanoparticles affects periphyton community structure and function
Gil-Allué, C., Tlili, A., Schirmer, K., Gessner, M. O., & Behra, R. (2018). Long-term exposure to silver nanoparticles affects periphyton community structure and function. Environmental Science: Nano, 5(6), 1397-1407. https://doi.org/10.1039/C8EN00132D
Importance of toxicokinetics to assess the utility of zebrafish larvae as model for psychoactive drug screening using meta-chlorophenylpiperazine (mCPP) as example
Kirla, K. T., Groh, K. J., Poetzsch, M., Banote, R. K., Stadnicka-Michalak, J., Eggen, R. I. L., … Kraemer, T. (2018). Importance of toxicokinetics to assess the utility of zebrafish larvae as model for psychoactive drug screening using meta-chlorophenylpiperazine (mCPP) as example. Frontiers in Pharmacology, 9, 414 (12 pp.). https://doi.org/10.3389/fphar.2018.00414
Nanomaterials in the environment: behavior, fate, bioavailability, and effects—an updated review
Lead, J. R., Batley, G. E., Alvarez, P. J. J., Croteau, M. N., Handy, R. D., McLaughlin, M. J., … Schirmer, K. (2018). Nanomaterials in the environment: behavior, fate, bioavailability, and effects—an updated review. Environmental Toxicology and Chemistry, 37(8), 2029-2063. https://doi.org/10.1002/etc.4147
A fish intestinal barrier model to assess the interaction with chemicals &lt;em&gt;in vitro&lt;/em&gt;
Schug, H. (2018). A fish intestinal barrier model to assess the interaction with chemicals in vitro (Doctoral dissertation). École polytechnique fédérale de Lausanne, Lausanne, 207 p.
TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an <i>in vitro</i> intestinal fish cell barrier
Schug, H., Begnaud, F., Debonneville, C., Berthaud, F., Gimeno, S., & Schirmer, K. (2018). TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an in vitro intestinal fish cell barrier. Analytical Methods, 10(36), 4394-4403. https://doi.org/10.1039/C8AY01253A
 

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