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Systems toxicology approach for testing chemical cardiotoxicity in larval zebrafish
Li, R., Zupanic, A., Talikka, M., Belcastro, V., Madan, S., Dörpinghaus, J., … Hoeng, J. (2020). Systems toxicology approach for testing chemical cardiotoxicity in larval zebrafish. Chemical Research in Toxicology, 33(10), 2550-2564. https://doi.org/10.1021/acs.chemrestox.0c00095
Characterization of the mercapturic acid pathway, an important phase II biotransformation route, in a zebrafish embryo cell line
Tierbach, A., Groh, K. J., Schoenenberger, R., Schirmer, K., & Suter, M. J. F. (2020). Characterization of the mercapturic acid pathway, an important phase II biotransformation route, in a zebrafish embryo cell line. Chemical Research in Toxicology (9 pp.). https://doi.org/10.1021/acs.chemrestox.0c00315
Systems toxicology approach to understand the kinetics of benzo(a)pyrene uptake, biotransformation, and dna adduct formation in a liver cell model
Madureira, D. J., Weiss, F. T., Van Midwoud, P., Helbling, D. E., Sturla, S. J., & Schirmer, K. (2014). Systems toxicology approach to understand the kinetics of benzo(a)pyrene uptake, biotransformation, and dna adduct formation in a liver cell model. Chemical Research in Toxicology, 27(3), 443-453. https://doi.org/10.1021/tx400446q
Systems toxicology: from basic research to risk assessment
Sturla, S. J., Boobis, A. R., FitzGerald, R. E., Hoeng, J., Kavlock, R. J., Schirmer, K., … Peitsch, M. C. (2014). Systems toxicology: from basic research to risk assessment. Chemical Research in Toxicology, 27(3), 314-329. https://doi.org/10.1021/tx400410s
Biotransformation pathways of biocides and pharmaceuticals in freshwater crustaceans based on structure elucidation of metabolites using high resolution mass spectrometry
Jeon, J., Kurth, D., & Hollender, J. (2013). Biotransformation pathways of biocides and pharmaceuticals in freshwater crustaceans based on structure elucidation of metabolites using high resolution mass spectrometry. Chemical Research in Toxicology, 26(3), 313-324. https://doi.org/10.1021/tx300457f
Protein and lipid binding parameters in rainbow trout (<i>Oncorhynchus mykiss</i>) blood and liver fractions to extrapolate from an <i>in Vitro</i> metabolic degradation assay to <i>in Vivo</i> bioaccumulation potential of hydrophobic organic chemicals
Escher, B. I., Cowan-Ellsberry, C. E., Dyer, S., Embry, M. R., Erhardt, S., Halder, M., … Nichols, J. (2011). Protein and lipid binding parameters in rainbow trout (Oncorhynchus mykiss) blood and liver fractions to extrapolate from an in Vitro metabolic degradation assay to in Vivo bioaccumulation potential of hydrophobic organic chemicals. Chemical Research in Toxicology, 24(7), 1134-1143. https://doi.org/10.1021/tx200114y
Development of a partition-controlled dosing system for cell assays
Kramer, N. I., Busser, F. J. M., Oosterwijk, M. T. T., Schirmer, K., Escher, B. I., & Hermens, J. L. M. (2010). Development of a partition-controlled dosing system for cell assays. Chemical Research in Toxicology, 23(11), 1806-1814. https://doi.org/10.1021/tx1002595
Toward a class-independent quantitative structure-activity relationship model for uncouplers of oxidative phosphorylation
Spycher, S., Smejtek, P., Netzeva, T. I., & Escher, B. I. (2008). Toward a class-independent quantitative structure-activity relationship model for uncouplers of oxidative phosphorylation. Chemical Research in Toxicology, 21(4), 911-927. https://doi.org/10.1021/tx700391f
A quantitative structure-activity relationship model for the intrinsic activity of uncouplers of oxidative phosphorylation
Spycher, S., Escher, B. I., & Gasteiger, J. (2005). A quantitative structure-activity relationship model for the intrinsic activity of uncouplers of oxidative phosphorylation. Chemical Research in Toxicology, 18, 1858-1867. https://doi.org/10.1021/tx050166j