In this thesis a preparation of selected Natural Deep Eutectic Solvents (NADES), which has been used as natural additives for polylactide processing in order to obtain novel PLA-blends. There-fore was investigated evaluation of the lubricating and/or plasticizing effect of additives while pro-cessing. Moreover to evaluate the effect of processing time in the degradation and homogeneity of PLA-blends comparison of different processing techniques has been done. Samples were employed to determine the effect of different additive concentrations on the me-chanical and thermal properties of studied blends. Additionally study of the isothermal crystallization of neat PLA and of promising PLA-blends has been done to define the best crystallization temperature as well as the Avrami’s kinetic constants.