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Investigating the effects of differently produced synthetic amorphous silica (E 551) on the integrity and functionality of the human intestinal barrier using an advanced in vitro co-culture model
Hempt, C., Hirsch, C., Hannig, Y., Rippl, A., Wick, P., & Buerki-Thurnherr, T. (2021). Investigating the effects of differently produced synthetic amorphous silica (E 551) on the integrity and functionality of the human intestinal barrier using an advanced in vitro co-culture model. Archives of Toxicology, 95, 837-852. https://doi.org/10.1007/s00204-020-02957-2
Template-free synthesis of hybrid silica nanoparticle with functionalized mesostructure for efficient methylene blue removal
Parida, D., Salmeia, K. A., Sadeghpour, A., Zhao, S., Maurya, A. K., Assaf, K. I., … Gaan, S. (2021). Template-free synthesis of hybrid silica nanoparticle with functionalized mesostructure for efficient methylene blue removal. Materials and Design, 201, 109494 (10 pp.). https://doi.org/10.1016/j.matdes.2021.109494
A novel approach to increase robustness, precision and high-throughput capacity of single cell gel electrophoresis
Cassano, J. C., Roesslein, M., Kaufmann, R., Luethi, T., Schicht, O., Wick, P., & Hirsch, C. (2020). A novel approach to increase robustness, precision and high-throughput capacity of single cell gel electrophoresis. ALTEX: Alternatives to Animal Experimentation, 37(1), 95-109. https://doi.org/10.14573/altex.1906252
Exploring flow cytometry-based micronucleus scoring for reliable nanomaterial genotoxicity assessment
Franz, P., Bürkle, A., Wick, P., & Hirsch, C. (2020). Exploring flow cytometry-based micronucleus scoring for reliable nanomaterial genotoxicity assessment. Chemical Research in Toxicology, 33(10), 2538-2549. https://doi.org/10.1021/acs.chemrestox.0c00071
Nanostructure generation during milk digestion in presence of cell culture models simulating the small intestine
Hempt, C., Gontsarik, M., Buerki-Thurnherr, T., Hirsch, C., & Salentinig, S. (2020). Nanostructure generation during milk digestion in presence of cell culture models simulating the small intestine. Journal of Colloid and Interface Science, 574, 430-440. https://doi.org/10.1016/j.jcis.2020.04.059
The impact of synthetic amorphous silica (E 551) on differentiated Caco-2 cells, a model for the human intestinal epithelium
Hempt, C., Kaiser, J. P., Scholder, O., Buerki-Thurnherr, T., Hofmann, H., Rippl, A., … Hirsch, C. (2020). The impact of synthetic amorphous silica (E 551) on differentiated Caco-2 cells, a model for the human intestinal epithelium. Toxicology in Vitro, 67, 104903 (14 pp.). https://doi.org/10.1016/j.tiv.2020.104903
Cause-and-effect analysis as a tool to improve the reproducibility of nanobioassays: four case studies
Petersen, E. J., Hirsch, C., Elliott, J. T., Krug, H. F., Aengenheister, L., Arif, A. T., … Roesslein, M. (2020). Cause-and-effect analysis as a tool to improve the reproducibility of nanobioassays: four case studies. Chemical Research in Toxicology, 33(5), 1039-1054. https://doi.org/10.1021/acs.chemrestox.9b00165
Human hazard potential of nanocellulose: quantitative insights from the literature
Stoudmann, N., Schmutz, M., Hirsch, C., Nowack, B., & Som, C. (2020). Human hazard potential of nanocellulose: quantitative insights from the literature. Nanotoxicology, 14(9), 1241-1257. https://doi.org/10.1080/17435390.2020.1814440
Innovative techniques and strategies for a reliable high-throughput genotoxicity assessment
Wick, P., Franz, P., Huber, S. M., & Hirsch, C. (2020). Innovative techniques and strategies for a reliable high-throughput genotoxicity assessment. Chemical Research in Toxicology, 33, 283-285. https://doi.org/10.1021/acs.chemrestox.9b00369
<em>In vitro</em> research reproducibility: keeping up high standards
Hirsch, C., & Schildknecht, S. (2019). In vitro research reproducibility: keeping up high standards. Frontiers in Pharmacology, 10, 1484 (9 pp.). https://doi.org/10.3389/fphar.2019.01484
Michael addition in reactive extrusion: a facile sustainable route to developing phosphorus based flame retardant materials
Simonetti, P., Nazir, R., Gooneie, A., Lehner, S., Jovic, M., Salmeia, K. A., … Gaan, S. (2019). Michael addition in reactive extrusion: a facile sustainable route to developing phosphorus based flame retardant materials. Composites Part B: Engineering, 178, 107470 (10 pp.). https://doi.org/10.1016/j.compositesb.2019.107470
Interference of engineered nanomaterials in flow cytometry: a case study
Bohmer, N., Rippl, A., May, S., Walter, A., Heo, M. B., Kwak, M., … Hirsch, C. (2018). Interference of engineered nanomaterials in flow cytometry: a case study. Colloids and Surfaces B: Biointerfaces, 172, 635-645. https://doi.org/10.1016/j.colsurfb.2018.09.021
Single exposure to aerosolized graphene oxide and graphene nanoplatelets did not initiate an acute biological response in a 3D human lung model
Drasler, B., Kucki, M., Delhaes, F., Buerki-Thurnherr, T., Vanhecke, D., Korejwo, D., … Wick, P. (2018). Single exposure to aerosolized graphene oxide and graphene nanoplatelets did not initiate an acute biological response in a 3D human lung model. Carbon, 137, 125-135. https://doi.org/10.1016/j.carbon.2018.05.012
Catechin loaded PLGA submicron-sized fibers reduce levels of reactive oxygen species induced by MWCNT <i>in vitro</i>
Ghitescu, R. E., Popa, A. M., Schipanski, A., Hirsch, C., Yazgan, G., Popa, V. I., … Fortunato, G. (2018). Catechin loaded PLGA submicron-sized fibers reduce levels of reactive oxygen species induced by MWCNT in vitro. European Journal of Pharmaceutics and Biopharmaceutics, 122, 78-86. https://doi.org/10.1016/j.ejpb.2017.10.009
The effect of different engineered nanomaterials (ENMs) on DNA damage and repair pathways
May, S. (2018). The effect of different engineered nanomaterials (ENMs) on DNA damage and repair pathways [Doctoral dissertation]. Universität Konstanz.
Transient DNA damage following exposure to gold nanoparticles
May, S., Hirsch, C., Rippl, A., Bohmer, N., Kaiser, J. P., Diener, L., … Wick, P. (2018). Transient DNA damage following exposure to gold nanoparticles. Nanoscale, 10(33), 15723-15735. https://doi.org/10.1039/C8NR03612H
Comprehensive study on flame retardant polyesters from phosphorus additives
Salmeia, K. A., Gooneie, A., Simonetti, P., Nazir, R., Kaiser, J. P., Rippl, A., … Gaan, S. (2018). Comprehensive study on flame retardant polyesters from phosphorus additives. Polymer Degradation and Stability, 155, 22-34. https://doi.org/10.1016/j.polymdegradstab.2018.07.006
Toward achieving harmonization in a nanocytotoxicity assay measurement through an interlaboratory comparison study
Elliott, J. T., Rösslein, M., Song, N. W., Toman, B., Kinsner-Ovaskainen, A., Maniratanachote, R., … Wick, P. (2017). Toward achieving harmonization in a nanocytotoxicity assay measurement through an interlaboratory comparison study. ALTEX: Alternatives to Animal Experimentation, 34(2), 201-218. https://doi.org/10.14573/altex.1605021
Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants
Hirsch, C., Striegl, B., Mathes, S., Adlhart, C., Edelmann, M., Bono, E., … Schildknecht, S. (2017). Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants. Archives of Toxicology, 91(1), 407-425. https://doi.org/10.1007/s00204-016-1680-4
Uptake of label-free graphene oxide by Caco-2 cells is dependent on the cell differentiation status
Kucki, M., Diener, L., Bohmer, N., Hirsch, C., Krug, H. F., Palermo, V., & Wick, P. (2017). Uptake of label-free graphene oxide by Caco-2 cells is dependent on the cell differentiation status. Journal of Nanobiotechnology, 15(1), 46 (18 pp.). https://doi.org/10.1186/s12951-017-0280-7