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Transcriptomic profiling reveals differential cellular response to copper oxide nanoparticles and polystyrene nanoplastics in perfused human placenta
Chortarea, S., Gupta, G., Saarimäki, L. A., Netkueakul, W., Manser, P., Aengenheister, L., … Buerki-Thurnherr, T. (2023). Transcriptomic profiling reveals differential cellular response to copper oxide nanoparticles and polystyrene nanoplastics in perfused human placenta. Environment International, 177, 108015 (15 pp.). https://doi.org/10.1016/j.envint.2023.108015
Differences and interactions in placental manganese and iron transfer across an in vitro model of human villous trophoblasts
Michaelis, V., Aengenheister, L., Tuchtenhagen, M., Rinklebe, J., Ebert, F., Schwerdtle, T., … Bornhorst, J. (2022). Differences and interactions in placental manganese and iron transfer across an in vitro model of human villous trophoblasts. International Journal of Molecular Sciences, 23(6), 3296 (18 pp.). https://doi.org/10.3390/ijms23063296
Addressing microchimerism in pregnancy by <em>ex vivo</em> human placenta perfusion
Murrieta-Coxca, J. M., Aengenheister, L., Schmidt, A., Markert, U. R., Buerki-Thurnherr, T., & Morales-Prieto, D. M. (2022). Addressing microchimerism in pregnancy by ex vivo human placenta perfusion. Placenta, 117, 78-86. https://doi.org/10.1016/j.placenta.2021.10.004
<em>Ex vivo</em> dual perfusion of an isolated human placenta cotyledon: towards protocol standardization and improved inter-centre comparability
Schneider, H., Albrecht, C., Ahmed, M. S., Broekhuizen, M., Aengenheister, L., Buerki-Thurnherr, T., … Brownbill, P. (2022). Ex vivo dual perfusion of an isolated human placenta cotyledon: towards protocol standardization and improved inter-centre comparability. Placenta, 126, 83-89. https://doi.org/10.1016/j.placenta.2022.05.003
Research on nanoparticles in human perfused placenta: state of the art and perspectives
Aengenheister, L., Favaro, R. R., Morales-Prieto, D. M., Furer, L. A., Gruber, M., Wadsack, C., … Buerki-Thurnherr, T. (2021). Research on nanoparticles in human perfused placenta: state of the art and perspectives. Placenta, 104, 199-207. https://doi.org/10.1016/j.placenta.2020.12.014
Label-free detection of uptake, accumulation, and translocation of diesel exhaust particles in ex vivo perfused human placenta
Bongaerts, E., Aengenheister, L., Dugershaw, B. B., Manser, P., Roeffaers, M. B. J., Ameloot, M., … Buerki-Thurnherr, T. (2021). Label-free detection of uptake, accumulation, and translocation of diesel exhaust particles in ex vivo perfused human placenta. Journal of Nanobiotechnology, 19(1), 144 (13 pp.). https://doi.org/10.1186/s12951-021-00886-5
Microfluidic co‐culture platform to recapitulate the maternal-placental-embryonic axis
Boos, J. A., Misun, P. M., Brunoldi, G., Furer, L. A., Aengenheister, L., Modena, M., … Hierlemann, A. (2021). Microfluidic co‐culture platform to recapitulate the maternal-placental-embryonic axis. Advanced biology, 5(8), 2100609 (12 pp.). https://doi.org/10.1002/adbi.202100609
Scalable synthesis of ultrasmall metal oxide radio-enhancers outperforming gold
Gerken, L. R. H., Neuer, A. L., Gschwend, P. M., Keevend, K., Gogos, A., Anthis, A. H. C., … Herrmann, I. K. (2021). Scalable synthesis of ultrasmall metal oxide radio-enhancers outperforming gold. Chemistry of Materials, 33(9), 3098-3112. https://doi.org/10.1021/acs.chemmater.0c04565
Fetal exposure to environmental chemicals; insights from placental perfusion studies
Mathiesen, L., Buerki-Thurnherr, T., Pastuschek, J., Aengenheister, L., & Knudsen, L. E. (2021). Fetal exposure to environmental chemicals; insights from placental perfusion studies. Placenta, 106, 58-66. https://doi.org/10.1016/j.placenta.2021.01.025
Recent insights on indirect mechanisms in developmental toxicity of nanomaterials
Dugershaw, B. B., Aengenheister, L., Schmidt Kjølner Hansen, S., Sørig Hougaard, K., & Buerki-Thurnherr, T. (2020). Recent insights on indirect mechanisms in developmental toxicity of nanomaterials. Particle and Fibre Toxicology, 17(1), 31 (22 pp.). https://doi.org/10.1186/s12989-020-00359-x
Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor &lt;em&gt;α&lt;/em&gt;
Inderbinen, S. G., Engeli, R. T., Rohrer, S. R., Di Renzo, E., Aengenheister, L., Buerki-Thurnherr, T., & Odermatt, A. (2020). Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α. Toxicology Letters, 322, 39-49. https://doi.org/10.1016/j.toxlet.2020.01.001
Cause-and-effect analysis as a tool to improve the reproducibility of nanobioassays: four case studies
Petersen, E. J., Hirsch, C., Elliott, J. T., Krug, H. F., Aengenheister, L., Arif, A. T., … Roesslein, M. (2020). Cause-and-effect analysis as a tool to improve the reproducibility of nanobioassays: four case studies. Chemical Research in Toxicology, 33(5), 1039-1054. https://doi.org/10.1021/acs.chemrestox.9b00165
Investigating the accumulation and translocation of titanium dioxide nanoparticles with different surface modifications in static and dynamic human placental transfer models
Aengenheister, L., Batbajar Dugershaw, B., Manser, P., Wichser, A., Schoenenberger, R., Wick, P., … Buerki-Thurnherr, T. (2019). Investigating the accumulation and translocation of titanium dioxide nanoparticles with different surface modifications in static and dynamic human placental transfer models. European Journal of Pharmaceutics and Biopharmaceutics, 142, 488-497. https://doi.org/10.1016/j.ejpb.2019.07.018
Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models &lt;em&gt;in vitro&lt;/em&gt;
Hesler, M., Aengenheister, L., Ellinger, B., Drexel, R., Straskraba, S., Jost, C., … Kohl, Y. (2019). Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitro. Toxicology in Vitro, 61, 104610 (15 pp.). https://doi.org/10.1016/j.tiv.2019.104610
An advanced human <i>in vitro</i> co-culture model for translocation studies across the placental barrier
Aengenheister, L., Keevend, K., Muoth, C., Schönenberger, R., Diener, L., Wick, P., & Buerki-Thurnherr, T. (2018). An advanced human in vitro co-culture model for translocation studies across the placental barrier. Scientific Reports, 8(1), 5388 (12 pp.). https://doi.org/10.1038/s41598-018-23410-6
Gold nanoparticle distribution in advanced in vitro and ex vivo human placental barrier models
Aengenheister, L., Dietrich, D., Sadeghpour, A., Manser, P., Diener, L., Wichser, A., … Buerki-Thurnherr, T. (2018). Gold nanoparticle distribution in advanced in vitro and ex vivo human placental barrier models. Journal of Nanobiotechnology, 16(1), 79 (16 pp.). https://doi.org/10.1186/s12951-018-0406-6
Risks and opportunities of nanomaterial exposure during pregnancy: from placental uptake and translocation to fetal consequences
Aengenheister, L. (2018). Risks and opportunities of nanomaterial exposure during pregnancy: from placental uptake and translocation to fetal consequences [Doctoral dissertation, ETH Zurich].
Developmental toxicity of nanomaterials. Need for a better understanding of indirect effects
Buerki-Thurnherr, T., Schaepper, K., Aengenheister, L., & Wick, P. (2018). Developmental toxicity of nanomaterials. Need for a better understanding of indirect effects. Chemical Research in Toxicology, 31(8), 641-642. https://doi.org/10.1021/acs.chemrestox.8b00177
Prenatal exposure to TiO<sub>2</sub> nanoparticles in mice causes behavioral deficits with relevance to autism spectrum disorder and beyond
Notter, T., Aengenheister, L., Weber-Stadlbauer, U., Naegeli, H., Wick, P., Meyer, U., & Buerki-Thurnherr, T. (2018). Prenatal exposure to TiO2 nanoparticles in mice causes behavioral deficits with relevance to autism spectrum disorder and beyond. Translational Psychiatry, 8(1), 193 (10 pp.). https://doi.org/10.1038/s41398-018-0251-2
Nanoparticle transport across the placental barrier: pushing the field forward!
Muoth, C., Aengenheister, L., Kucki, M., Wick, P., & Buerki-Thurnherr, T. (2016). Nanoparticle transport across the placental barrier: pushing the field forward!. Nanomedicine, 11(8), 941-957. https://doi.org/10.2217/nnm-2015-0012