Designing dual inhibitors of anaplastic lymphoma kinase (ALK) and bromodomain-4 (BRD4) by tuning kinase selectivity

Watts E, Heidenreich D, Tucker E, Raab M, Strebhardt K, Chesler L, Knapp S, Bellenie B & Hoelder S
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Watts, E., Heidenreich, D., Tucker, E., Raab, M., Strebhardt, K., Chesler, L., … Hoelder, S. (2019). Designing dual inhibitors of anaplastic lymphoma kinase (ALK) and bromodomain-4 (BRD4) by tuning kinase selectivity. Journal of Medicinal Chemistry, 62(5), 2618-2637. https://doi.org/10.1021/acs.jmedchem.8b01947