Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow

Fradera X, Methot JL, Achab A, Christopher M, Altman MD, Zhou H, McGowan MA, Kattar SD, Wilson K, Garcia Y, Augustin MA, Lesburg CA, Shah S, Goldenblatt P & Katz JD
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Fradera, X., Methot, J. L., Achab, A., Christopher, M., Altman, M. D., Zhou, H., … Katz, J. D. (2019). Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow. Bioorganic and Medicinal Chemistry Letters, 29(18), 2575-2580. https://doi.org/10.1016/j.bmcl.2019.08.004