Discovery and structure-based optimization of next-generation reversible methionine aminopeptidase-2 (MetAP-2) inhibitors

Heinrich T, Seenisamy J, Blume B, Bomke J, Calderini M, Eckert U, Friese-Hamim M, Kohl R, Lehmann M, Leuthner B, Musil D, Rohdich F & Zenke FT
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Heinrich, T., Seenisamy, J., Blume, B., Bomke, J., Calderini, M., Eckert, U., … Zenke, F. T. (2019). Discovery and structure-based optimization of next-generation reversible methionine aminopeptidase-2 (MetAP-2) inhibitors. Journal of Medicinal Chemistry, 62(10), 5025-5039. https://doi.org/10.1021/acs.jmedchem.9b00041