De-novo design of cereblon (CRBN) effectors guided by natural hydrolysis products of thalidomide derivatives

Heim C, Pliatsika D, Mousavizadeh F, Bär K, Hernandez Alvarez B, Giannis A & Hartmann MD
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Heim, C., Pliatsika, D., Mousavizadeh, F., Bär, K., Hernandez Alvarez, B., Giannis, A., & Hartmann, M. D. (2019). De-novo design of cereblon (CRBN) effectors guided by natural hydrolysis products of thalidomide derivatives. Journal of Medicinal Chemistry, 62(14), 6615-6629. https://doi.org/10.1021/acs.jmedchem.9b00454