Characterization of covalent pyrazolopyrimidine-MKK7 complexes and a report on a unique DFG-in/Leu-in conformation of mitogen-activated protein kinase kinase 7 (MKK7)

Wolle P, Engel J, Smith S, Goebel L, Hennes E, Lategahn J & Rauh D
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Wolle, P., Engel, J., Smith, S., Goebel, L., Hennes, E., Lategahn, J., & Rauh, D. (2019). Characterization of covalent pyrazolopyrimidine-MKK7 complexes and a report on a unique DFG-in/Leu-in conformation of mitogen-activated protein kinase kinase 7 (MKK7). Journal of Medicinal Chemistry, 62(11), 5541-5546. https://doi.org/10.1021/acs.jmedchem.9b00472