Start selective and rigidify: the discovery path toward a next generation of EGFR tyrosine kinase inhibitors

Engelhardt H, Böse D, Petronczki M, Scharn D, Bader G, Baum A, Bergner A, Chong E, Döbel S, Egger G, Engelhardt C, Ettmayer P, Fuchs JE, Gerstberger T, Gonnella N, Grimm A, Grondal E, Haddad N, Hopfgartner B, Kousek R, Krawiec M, Kriz M, Lamarre L, Leung J, Mayer M, Patel ND, Peric Simov B, Reeves JT, Schnitzer R, Schrenk A, Sharps B, Solca F, Stadtmüller H, Tan Z, Wunberg T, Zoephel A & McConnell DB
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Engelhardt, H., Böse, D., Petronczki, M., Scharn, D., Bader, G., Baum, A., … McConnell, D. B. (2019). Start selective and rigidify: the discovery path toward a next generation of EGFR tyrosine kinase inhibitors. Journal of Medicinal Chemistry, 62(22), 10272-10293. https://doi.org/10.1021/acs.jmedchem.9b01169