Targeting cavity-creating p53 cancer mutations with small-molecule stabilizers: the Y220X paradigm

Bauer MR, Krämer A, Settanni G, Jones RN, Ni X, Khan Tareque R, Fersht AR, Spencer J & Joerger AC
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Bauer, M. R., Krämer, A., Settanni, G., Jones, R. N., Ni, X., Khan Tareque, R., … Joerger, A. C. (2020). Targeting cavity-creating p53 cancer mutations with small-molecule stabilizers: the Y220X paradigm. ACS Chemical Biology, 15(3), 657-668. https://doi.org/10.1021/acschembio.9b00748