Structure-guided design of substituted biphenyl butanoic acid derivatives as neprilysin inhibitors

Kawanami T, Karki RG, Cody E, Liu Q, Liang G, Ksander GM, Rigel DF, Schiering N, Gong Y, Coppola GM, Iwaki Y, Sun R, Neubert A, Fan L, Ingles S, D’Arcy A, Villard F, Ramage P, Jeng AY, Leung-Chu J, Liu J, Beil M, Fu F, Chen W, Cumin F, Wiesmann C & Mogi M
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Kawanami, T., Karki, R. G., Cody, E., Liu, Q., Liang, G., Ksander, G. M., … Mogi, M. (2020). Structure-guided design of substituted biphenyl butanoic acid derivatives as neprilysin inhibitors. ACS Medicinal Chemistry Letters, 11(2), 188-194. https://doi.org/10.1021/acsmedchemlett.9b00578