A precisely positioned MED12 activation helix stimulates CDK8 kinase activity

Klatt F, Leitner A, Kim IV, Ho-Xuan H, Schneider EV, Langhammer F, Weinmann R, Müller MR, Huber R, Meister G & Kuhn C-D
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Klatt, F., Leitner, A., Kim, I. V., Ho-Xuan, H., Schneider, E. V., Langhammer, F., … Kuhn, C. D. (2020). A precisely positioned MED12 activation helix stimulates CDK8 kinase activity. Proceedings of the National Academy of Sciences of the United States of America PNAS, 117(6), 2894-2905. https://doi.org/10.1073/pnas.1917635117