Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis

Chen F, Lukat P, Iqbal AA, Saile K, Kaever V, van den Heuvel J, Blankenfeldt W, Büssow K & Pessler F
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Chen, F., Lukat, P., Iqbal, A. A., Saile, K., Kaever, V., van den Heuvel, J., … Pessler, F. (2019). Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis. Proceedings of the National Academy of Sciences of the United States of America PNAS, 116(41), 20644-20654. https://doi.org/10.1073/pnas.1908770116