Structure-based macrocyclization of substrate analogue NS2B-NS3 protease inhibitors of Zika, West Nile and dengue viruses

Braun NJ, Quek JP, Huber S, Kouretova J, Rogge D, Lang-Henkel H, Cheong EZK, Chew BLA, Heine A, Luo D & Steinmetzer T
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Braun, N. J., Quek, J. P., Huber, S., Kouretova, J., Rogge, D., Lang-Henkel, H., … Steinmetzer, T. (2020). Structure-based macrocyclization of substrate analogue NS2B-NS3 protease inhibitors of Zika, West Nile and dengue viruses. ChemMedChem, 15(15), 1439-1452. https://doi.org/10.1002/cmdc.202000237