Diazaspirononane nonsaccharide inhibitors of O-GlcNAcase (OGA) for the treatment of neurodegenerative disorders

Martínez-Viturro CM, Trabanco AA, Royes J, Fernández E, Tresadern G, Vega JA, del Cerro A, Delgado F, Garciá Molina A, Tovar F, Shaffer P, Ebneth A, Bretteville A, Mertens L, Somers M, Alonso JM & Bartolomé-Nebreda JM
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Martínez-Viturro, C. M., Trabanco, A. A., Royes, J., Fernández, E., Tresadern, G., Vega, J. A., … Bartolomé-Nebreda, J. M. (2020). Diazaspirononane nonsaccharide inhibitors of O-GlcNAcase (OGA) for the treatment of neurodegenerative disorders. Journal of Medicinal Chemistry, 63(22), 14017-14044. https://doi.org/10.1021/acs.jmedchem.0c01479