Oxaprozin analogues as selective RXR agonists with superior properties and pharmacokinetics

Schierle S, Chaikuad A, Lillich FF, Ni X, Woltersdorf S, Schallmayer E, Renelt B, Ronchetti R, Knapp S, Proschak E & Merk D
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Schierle, S., Chaikuad, A., Lillich, F. F., Ni, X., Woltersdorf, S., Schallmayer, E., … Merk, D. (2021). Oxaprozin analogues as selective RXR agonists with superior properties and pharmacokinetics. Journal of Medicinal Chemistry, 64(8), 5123-5136. https://doi.org/10.1021/acs.jmedchem.1c00235