Lignin is an abundant natural polymer obtained from lignocellulosic biomass and rich in aromatic substructures. When efficiently depolymerized, it has great potential in the production of value-added chemicals. Fast pyrolysis is a promising depolymerization method, but current studies focus mainly on small quantities of lignin. To determine the potential for upscaling, we evaluated the systems used in the most relevant unit operations of fast pyrolysis of lignin. Fluidized-bed reactors have the most potential. It would be beneficial to combine them with the following: slug injectors for feeding, hot particle filters, cyclones, and fractional condensation for product separation and recovery. Moreover, upgrading lignin pyrolysis oil would allow reaching the necessary quality parameters for particular applications.