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Early prediction of long-term tactile object recognition performance after sensorimotor stroke
Abela, E., Missimer, J. H., Pastore-Wapp, M., Krammer, W., Wiest, R., & Weder, B. J. (2019). Early prediction of long-term tactile object recognition performance after sensorimotor stroke. Cortex, 115, 264-279. https://doi.org/10.1016/j.cortex.2019.01.018
Microtubule minus-end regulation at a glance
Akhmanova, A., & Steinmetz, M. O. (2019). Microtubule minus-end regulation at a glance. Journal of Cell Science, 132(11), jcs227850 (7 pp.). https://doi.org/10.1242/jcs.227850
Structural determinants of microtubule minus end preference in CAMSAP CKK domains
Atherton, J., Luo, Y., Xiang, S., Yang, C., Rai, A., Jiang, K., … Moores, C. A. (2019). Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nature Communications, 10(1), 5236 (16 pp.). https://doi.org/10.1038/s41467-019-13247-6
Long-wavelength native-SAD phasing: opportunities and challenges
Basu, S., Olieric, V., Leonarski, F., Matsugaki, N., Kawano, Y., Takashi, T., … Wang, M. (2019). Long-wavelength native-SAD phasing: opportunities and challenges. IUCrJ, 6(3), 1-14. https://doi.org/10.1107/S2052252519002756
Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm
Bliven, S. E., Lafita, A., Rose, P. W., Capitani, G., Prlić, A., & Bourne, P. E. (2019). Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm. PLoS Computational Biology, 15(4), e1006842 (18 pp.). https://doi.org/10.1371/journal.pcbi.1006842
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
Brindisi, M., Ulivieri, C., Alfano, G., Gemma, S., de Asís Balaguer, F., Khan, T., … Brogi, S. (2019). Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents. European Journal of Medicinal Chemistry, 162, 290-320. https://doi.org/10.1016/j.ejmech.2018.11.004
Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins
Chalupska, D., Różycki, B., Humpolickova, J., Faltova, L., Klima, M., & Boura, E. (2019). Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins. Scientific Reports, 9(1), 567 (11 pp.). https://doi.org/10.1038/s41598-018-37158-6
Remote control of microtubule plus-end dynamics and function from the minus-end
Chen, X., Widmer, L. A., Stangier, M. M., Steinmetz, M. O., Stelling, J., & Barral, Y. (2019). Remote control of microtubule plus-end dynamics and function from the minus-end. eLife, 8, e48627 (32 pp.). https://doi.org/10.7554/eLife.48627
Structural basis of colchicine-site targeting acylhydrazones active against multidrug-resistant acute lymphoblastic leukemia
Cury, N. M., Mühlethaler, T., Laranjeira, A. B. A., Canevarolo, R. R., Zenatti, P. P., Lucena-Agell, D., … Yunes, J. A. (2019). Structural basis of colchicine-site targeting acylhydrazones active against multidrug-resistant acute lymphoblastic leukemia. iScience, 21, 95-109. https://doi.org/10.1016/j.isci.2019.10.003
Tetrahydroisoquinoline sulfamates as potent microtubule disruptors: synthesis, antiproliferative and antitubulin activity of dichlorobenzyl-based derivatives, and a Tubulin cocrystal structure.
Dohle, W., Prota, A. E., Menchon, G., Hamel, E., Steinmetz, M. O., & Potter, B. V. L. (2019). Tetrahydroisoquinoline sulfamates as potent microtubule disruptors: synthesis, antiproliferative and antitubulin activity of dichlorobenzyl-based derivatives, and a Tubulin cocrystal structure. ACS Omega, 4, 755-764. https://doi.org/10.1021/acsomega.8b02879
Conformational properties of the chemotherapeutic drug analogue Epothilone A: how to model a flexible protein ligand using scarcely available experimental data
Dolenc, J., van Gunsteren, W. F., Prota, A. E., Steinmetz, M. O., & Missimer, J. H. (2019). Conformational properties of the chemotherapeutic drug analogue Epothilone A: how to model a flexible protein ligand using scarcely available experimental data. Journal of Chemical Information and Modeling, 59(5), 2218-2230. https://doi.org/10.1021/acs.jcim.9b00171
The two-photon reversible reaction of the bistable jumping spider rhodopsin-1
Ehrenberg, D., Varma, N., Deupi, X., Koyanagi, M., Terakita, A., Schertler, G. F. X., … Lesca, E. (2019). The two-photon reversible reaction of the bistable jumping spider rhodopsin-1. Biophysical Journal, 116(7), 1248-1258. https://doi.org/10.1016/j.bpj.2019.02.025
Crystal structure of a heterotetrameric katanin p60:p80 complex
Faltova, L., Jiang, K., Frey, D., Wu, Y., Capitani, G., Prota, A. E., … Kammerer, R. A. (2019). Crystal structure of a heterotetrameric katanin p60:p80 complex. Structure, 27(9), 1375-1383.e3. https://doi.org/10.1016/j.str.2019.07.002
Insights into the basal activity and activation mechanism of the β1 adrenergic receptor using native mass spectrometry
Gavriilidou, A. F. M., Hunziker, H., Mayer, D., Vuckovic, Z., Veprintsev, D. B., & Zenobi, R. (2019). Insights into the basal activity and activation mechanism of the β1 adrenergic receptor using native mass spectrometry. Journal of the American Society for Mass Spectrometry, 30(3), 529-537. https://doi.org/10.1007/s13361-018-2110-z
Licochalcone A protects the blood milk barrier integrity and relieves the inflammatory response in LPS-induced mastitis
Guo, W., Liu, B., Yin, Y., Kan, X., Gong, Q., Li, Y., … Liu, J. (2019). Licochalcone A protects the blood milk barrier integrity and relieves the inflammatory response in LPS-induced mastitis. Frontiers in Immunology, 10, 287 (14 pp.). https://doi.org/10.3389/fimmu.2019.00287
Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography
Górzny, M. Ł., Opara, N. L., Guzenko, V. A., Cadarso, V. J., Schift, H., Li, X. D., & Padeste, C. (2019). Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography. Micro and Nano Engineering, 3, 31-36. https://doi.org/10.1016/j.mne.2019.03.002
Arrestin-1 engineering facilitates complex stabilization with native rhodopsin
Haider, R. S., Wilhelm, F., Rizk, A., Mutt, E., Deupi, X., Peterhans, C., … Ostermaier, M. K. (2019). Arrestin-1 engineering facilitates complex stabilization with native rhodopsin. Scientific Reports, 9(1), 439 (13 pp.). https://doi.org/10.1038/s41598-018-36881-4
MAP7 family proteins regulate kinesin-1 recruitment and activation
Hooikaas, P. J., Martin, M., Mühlethaler, T., Kuijntjes, G. J., Peeters, C. A. E., Katrukha, E. A., … Akhmanova, A. (2019). MAP7 family proteins regulate kinesin-1 recruitment and activation. Journal of Cell Biology, 218(4), 1298-1318. https://doi.org/10.1083/jcb.201808065
Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7
Jaeger, K., Bruenle, S., Weinert, T., Guba, W., Muehle, J., Miyazaki, T., … Standfuss, J. (2019). Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7. Cell, 178(5), 1222-1230. https://doi.org/10.1016/j.cell.2019.07.028
GEF-H1 signaling upon microtubule destabilization is required for dendritic cell activation and specific anti-tumor responses
Kashyap, A. S., Fernandez-Rodriguez, L., Zhao, Y., Monaco, G., Trefny, M. P., Yoshida, N., … Zippelius, A. (2019). GEF-H1 signaling upon microtubule destabilization is required for dendritic cell activation and specific anti-tumor responses. Cell Reports, 28(13), 3367-3380.e1. https://doi.org/10.1016/j.celrep.2019.08.057
 

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