| Relevance of rhodopsin studies for GPCR activation
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| Production of GPCR and GPCR complexes for structure determination
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| Relation between sequence and structure in membrane proteins
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| Insights into congenital stationary night blindness based on the structure of G90D rhodopsin
Singhal, A., Ostermaier, M. K., Vishnivetskiy, S. A., Panneels, V., Homan, K. T., Tesmer, J. J. G., … Standfuss, J. (2013). Insights into congenital stationary night blindness based on the structure of G90D rhodopsin. EMBO Reports, 14(6), 520-526. https://doi.org/10.1038/embor.2013.44 |
| AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis.
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| Two alternative conformations of a voltage-gated sodium channel
Tsai, C. J., Tani, K., Irie, K., Hiroaki, Y., Shimomura, T., McMillan, D. G., … Li, X. D. (2013). Two alternative conformations of a voltage-gated sodium channel. Journal of Molecular Biology, 425(22), 4074-4088. https://doi.org/10.1016/j.jmb.2013.06.036 |
| Molecular signatures of G-protein-coupled receptors
Venkatakrishnan, A. J., Deupi, X., Lebon, G., Tate, C. G., Schertler, G. F., & Babu, M. M. (2013). Molecular signatures of G-protein-coupled receptors. Nature, 494(7436), 185-194. https://doi.org/10.1038/nature11896 |
| Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding
Vishnivetskiy, S. A., Ostermaier, M. K., Singhal, A., Panneels, V., Homan, K. T., Glukhova, A., … Gurevich, V. V. (2013). Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding. Cellular Signalling, 25(11), 2155-2162. https://doi.org/10.1016/j.cellsig.2013.07.009 |
| Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II
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| Structural insights into agonist-induced activation of G-protein-coupled receptors
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| Membranes
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| Preparation of an activated rhodopsin/transducin complex using a constitutively active mutant of rhodopsin
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