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  • (-) PSI Divisions = Biology and Chemistry BIO
  • (-) Publication Year = 2019 - 2019
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Long-wavelength native-SAD phasing: opportunities and challenges
Basu, S., Olieric, V., Leonarski, F., Matsugaki, N., Kawano, Y., Takashi, T., … Wang, M. (2019). Long-wavelength native-SAD phasing: opportunities and challenges. IUCrJ, 6(3), 1-14. https://doi.org/10.1107/S2052252519002756
Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm
Bliven, S. E., Lafita, A., Rose, P. W., Capitani, G., Prlić, A., & Bourne, P. E. (2019). Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm. PLoS Computational Biology, 15(4), e1006842 (18 pp.). https://doi.org/10.1371/journal.pcbi.1006842
Diastereomerically pure 6<em>R</em>- and 6<em>S</em>-3'-aza-2'-<sup>18</sup>F-fluoro-5-methyltetrahydrofolates show unprecedentedly high uptake in folate receptor-positive KB tumors
Boss, S. D., Müller, C., Siwowska, K., Schmid, R. M., Groehn, V., Schibli, R., & Ametamey, S. M. (2019). Diastereomerically pure 6R- and 6S-3'-aza-2'-18F-fluoro-5-methyltetrahydrofolates show unprecedentedly high uptake in folate receptor-positive KB tumors. Journal of Nuclear Medicine, 60(1), 135-141. https://doi.org/10.2967/jnumed.118.213314
Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins
Brandl, F., Merten, H., Zimmermann, M., Béhé, M., Zangemeister-Wittke, U., & Plückthun, A. (2019). Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins. Journal of Controlled Release, 307, 379-392. https://doi.org/10.1016/j.jconrel.2019.06.030
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
Brindisi, M., Ulivieri, C., Alfano, G., Gemma, S., de Asís Balaguer, F., Khan, T., … Brogi, S. (2019). Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents. European Journal of Medicinal Chemistry, 162, 290-320. https://doi.org/10.1016/j.ejmech.2018.11.004
Succinylated gelatin improves the theranostic potential of radiolabeled exendin-4 in insulinoma patients
Buitinga, M., Jansen, T., van der Kroon, I., Woliner-van der Weg, W., Boss, M., Janssen, M., … Gotthardt, M. (2019). Succinylated gelatin improves the theranostic potential of radiolabeled exendin-4 in insulinoma patients. Journal of Nuclear Medicine, 60(6), 812-816. https://doi.org/10.2967/jnumed.118.219980
The two-photon reversible reaction of the bistable jumping spider rhodopsin-1
Ehrenberg, D., Varma, N., Deupi, X., Koyanagi, M., Terakita, A., Schertler, G. F. X., … Lesca, E. (2019). The two-photon reversible reaction of the bistable jumping spider rhodopsin-1. Biophysical Journal, 116(7), 1248-1258. https://doi.org/10.1016/j.bpj.2019.02.025
Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography
Górzny, M. Ł., Opara, N. L., Guzenko, V. A., Cadarso, V. J., Schift, H., Li, X. D., & Padeste, C. (2019). Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography. Micro and Nano Engineering, 3, 31-36. https://doi.org/10.1016/j.mne.2019.03.002
Arrestin-1 engineering facilitates complex stabilization with native rhodopsin
Haider, R. S., Wilhelm, F., Rizk, A., Mutt, E., Deupi, X., Peterhans, C., … Ostermaier, M. K. (2019). Arrestin-1 engineering facilitates complex stabilization with native rhodopsin. Scientific Reports, 9(1), 439 (13 pp.). https://doi.org/10.1038/s41598-018-36881-4
High‐resolution SPECT imaging of stimuli‐responsive soft microrobots
Iacovacci, V., Blanc, A., Huang, H., Ricotti, L., Schibli, R., Menciassi, A., … Nelson, B. J. (2019). High‐resolution SPECT imaging of stimuli‐responsive soft microrobots. Small, 15(34), 1900709 (7 pp.). https://doi.org/10.1002/smll.201900709
Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7
Jaeger, K., Bruenle, S., Weinert, T., Guba, W., Muehle, J., Miyazaki, T., … Standfuss, J. (2019). Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7. Cell, 178(5), 1222-1230. https://doi.org/10.1016/j.cell.2019.07.028
Exendin-4 analogs in insulinoma theranostics
Jansen, T. J. P., van Lith, S. A. M., Boss, M., Brom, M., Joosten, L., Béhé, M., … Gotthardt, M. (2019). Exendin-4 analogs in insulinoma theranostics. Journal of Labelled Compounds and Radiopharmaceuticals, 62(10), 656-672. https://doi.org/10.1002/jlcr.3750
Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting
Kaeppeli, S. A. M., Jodal, A., Gotthardt, M., Schibli, R., & Behe, M. (2019). Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting. Molecular Pharmaceutics, 16(9), 3760-3769. https://doi.org/10.1021/acs.molpharmaceut.9b00271
Concentration‐dependent effects of dutasteride on prostate‐specific membrane antigen (PSMA) expression and uptake of <sup>177</sup>Lu‐PSMA‐617 in LNCaP cells
Kranzbühler, B., Salemi, S., Umbricht, C. A., Deberle, L. M., Müller, C., Burger, I. A., … Eberli, D. (2019). Concentration‐dependent effects of dutasteride on prostate‐specific membrane antigen (PSMA) expression and uptake of 177Lu‐PSMA‐617 in LNCaP cells. Prostate, 79(12), 1477-1483. https://doi.org/10.1002/pros.23868
Ferroelectric self-poling in GeTe films and crystals
Kriegner, D., Springholz, G., Richter, C., Pilet, N., Müller, E., Capron, M., … Krempaský, J. (2019). Ferroelectric self-poling in GeTe films and crystals. Crystals, 9(7), 335 (15 pp.). https://doi.org/10.3390/cryst9070335
Heavy atom labeling enables silanol defect visualization in silicalite-1 crystals
Li, T., Krumeich, F., Ihli, J., Ma, Z., Ishikawa, T., Pinar, A. B., & van Bokhoven, J. A. (2019). Heavy atom labeling enables silanol defect visualization in silicalite-1 crystals. Chemical Communications, 55(4), 482-485. https://doi.org/10.1039/c8cc07912a
Femtosecond phase-transition in hard x-ray excited bismuth
Makita, M., Vartiainen, I., Mohacsi, I., Caleman, C., Diaz, A., Jönsson, H. O., … David, C. (2019). Femtosecond phase-transition in hard x-ray excited bismuth. Scientific Reports, 9(1), 602 (7 pp.). https://doi.org/10.1038/s41598-018-36216-3
Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation
Mayer, D., Damberger, F. F., Samarasimhareddy, M., Feldmueller, M., Vuckovic, Z., Flock, T., … Veprintsev, D. B. (2019). Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation. Nature Communications, 10, 1261 (14 pp.). https://doi.org/10.1038/s41467-019-09204-y
Supramolecular architectures of molecularly thin yet robust free-standing layers
Moradi, M., Opara, N. L., Tulli, L. G., Wäckerlin, C., Dalgarno, S. J., Teat, S. J., … Shahgaldian, P. (2019). Supramolecular architectures of molecularly thin yet robust free-standing layers. Science Advances, 5(2), eaav4489 (7 pp.). https://doi.org/10.1126/sciadv.aav4489
An online resource for GPCR structure determination and analysis
Munk, C., Mutt, E., Isberg, V., Nikolajsen, L. F., Bibbe, J. M., Flock, T., … Gloriam, D. E. (2019). An online resource for GPCR structure determination and analysis. Nature Methods, 16(2), 151-162. https://doi.org/10.1038/s41592-018-0302-x