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  • (-) Publication Year = 2019 - 2019
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Microtubule minus-end regulation at a glance
Akhmanova, A., & Steinmetz, M. O. (2019). Microtubule minus-end regulation at a glance. Journal of Cell Science, 132(11), jcs227850 (7 pp.). https://doi.org/10.1242/jcs.227850
Long-wavelength native-SAD phasing: opportunities and challenges
Basu, S., Olieric, V., Leonarski, F., Matsugaki, N., Kawano, Y., Takashi, T., … Wang, M. (2019). Long-wavelength native-SAD phasing: opportunities and challenges. IUCrJ, 6(3), 1-14. https://doi.org/10.1107/S2052252519002756
Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm
Bliven, S. E., Lafita, A., Rose, P. W., Capitani, G., Prlić, A., & Bourne, P. E. (2019). Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm. PLoS Computational Biology, 15(4), e1006842 (18 pp.). https://doi.org/10.1371/journal.pcbi.1006842
Diastereomerically pure 6<em>R</em>- and 6<em>S</em>-3'-aza-2'-<sup>18</sup>F-fluoro-5-methyltetrahydrofolates show unprecedentedly high uptake in folate receptor-positive KB tumors
Boss, S. D., Müller, C., Siwowska, K., Schmid, R. M., Groehn, V., Schibli, R., & Ametamey, S. M. (2019). Diastereomerically pure 6R- and 6S-3'-aza-2'-18F-fluoro-5-methyltetrahydrofolates show unprecedentedly high uptake in folate receptor-positive KB tumors. Journal of Nuclear Medicine, 60(1), 135-141. https://doi.org/10.2967/jnumed.118.213314
Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins
Brandl, F., Merten, H., Zimmermann, M., Béhé, M., Zangemeister-Wittke, U., & Plückthun, A. (2019). Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins. Journal of Controlled Release, 307, 379-392. https://doi.org/10.1016/j.jconrel.2019.06.030
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
Brindisi, M., Ulivieri, C., Alfano, G., Gemma, S., de Asís Balaguer, F., Khan, T., … Brogi, S. (2019). Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents. European Journal of Medicinal Chemistry, 162, 290-320. https://doi.org/10.1016/j.ejmech.2018.11.004
Succinylated gelatin improves the theranostic potential of radiolabeled exendin-4 in insulinoma patients
Buitinga, M., Jansen, T., van der Kroon, I., Woliner-van der Weg, W., Boss, M., Janssen, M., … Gotthardt, M. (2019). Succinylated gelatin improves the theranostic potential of radiolabeled exendin-4 in insulinoma patients. Journal of Nuclear Medicine, 60(6), 812-816. https://doi.org/10.2967/jnumed.118.219980
Measurement of the <sup>43</sup>Sc production cross-section with a deuteron beam
Carzaniga, T. S., van der Meulen, N. P., Hasler, R., Kottler, C., Peier, P., Türler, A., … Braccini, S. (2019). Measurement of the 43Sc production cross-section with a deuteron beam. Applied Radiation and Isotopes, 145, 205-208. https://doi.org/10.1016/j.apradiso.2018.12.031
Remote control of microtubule plus-end dynamics and function from the minus-end
Chen, X., Widmer, L. A., Stangier, M. M., Steinmetz, M. O., Stelling, J., & Barral, Y. (2019). Remote control of microtubule plus-end dynamics and function from the minus-end. eLife, 8, e48627 (32 pp.). https://doi.org/10.7554/eLife.48627
Internal radiation dosimetry of a <sup>152</sup>Tb-labeled antibody in tumor-bearing mice
Cicone, F., Gnesin, S., Denoël, T., Stora, T., van der Meulen, N. P., Müller, C., … Prior, J. O. (2019). Internal radiation dosimetry of a 152Tb-labeled antibody in tumor-bearing mice. EJNMMI Research, 9, 53 (10 pp.). https://doi.org/10.1186/s13550-019-0524-7
Tetrahydroisoquinoline sulfamates as potent microtubule disruptors: synthesis, antiproliferative and antitubulin activity of dichlorobenzyl-based derivatives, and a Tubulin cocrystal structure.
Dohle, W., Prota, A. E., Menchon, G., Hamel, E., Steinmetz, M. O., & Potter, B. V. L. (2019). Tetrahydroisoquinoline sulfamates as potent microtubule disruptors: synthesis, antiproliferative and antitubulin activity of dichlorobenzyl-based derivatives, and a Tubulin cocrystal structure. ACS Omega, 4, 755-764. https://doi.org/10.1021/acsomega.8b02879
Conformational properties of the chemotherapeutic drug analogue Epothilone A: how to model a flexible protein ligand using scarcely available experimental data
Dolenc, J., van Gunsteren, W. F., Prota, A. E., Steinmetz, M. O., & Missimer, J. H. (2019). Conformational properties of the chemotherapeutic drug analogue Epothilone A: how to model a flexible protein ligand using scarcely available experimental data. Journal of Chemical Information and Modeling, 59(5), 2218-2230. https://doi.org/10.1021/acs.jcim.9b00171
The two-photon reversible reaction of the bistable jumping spider rhodopsin-1
Ehrenberg, D., Varma, N., Deupi, X., Koyanagi, M., Terakita, A., Schertler, G. F. X., … Lesca, E. (2019). The two-photon reversible reaction of the bistable jumping spider rhodopsin-1. Biophysical Journal, 116(7), 1248-1258. https://doi.org/10.1016/j.bpj.2019.02.025
Crystal structure of a heterotetrameric katanin p60:p80 complex
Faltova, L., Jiang, K., Frey, D., Wu, Y., Capitani, G., Prota, A. E., … Kammerer, R. A. (2019). Crystal structure of a heterotetrameric katanin p60:p80 complex. Structure, 27(9), 1375-1383.e3. https://doi.org/10.1016/j.str.2019.07.002
Insights into the basal activity and activation mechanism of the β1 adrenergic receptor using native mass spectrometry
Gavriilidou, A. F. M., Hunziker, H., Mayer, D., Vuckovic, Z., Veprintsev, D. B., & Zenobi, R. (2019). Insights into the basal activity and activation mechanism of the β1 adrenergic receptor using native mass spectrometry. Journal of the American Society for Mass Spectrometry, 30(3), 529-537. https://doi.org/10.1007/s13361-018-2110-z
Production and characterization of no-carrier-added <sup>161</sup>Tb as an alternative to the clinically-applied <sup>177</sup>Lu for radionuclide therapy
Gracheva, N., Müller, C., Talip, Z., Heinitz, S., Köster, U., Zeevaart, J. R., … van der Meulen, N. P. (2019). Production and characterization of no-carrier-added 161Tb as an alternative to the clinically-applied 177Lu for radionuclide therapy. EJNMMI Radiopharmacy and Chemistry, 4, 12 (16 pp.). https://doi.org/10.1186/s41181-019-0063-6
L1CAM. Ein vielversprechendes Zellmembranprotein für therapeutische Interventionen
Grünberg, J., & Terraneo, N. (2019). L1CAM. Ein vielversprechendes Zellmembranprotein für therapeutische Interventionen. Leading Opinions Hämatologie & Onkologie.
Structure and transformation of bacteriophage A511 baseplate and tail upon infection of <em>Listeria </em>cells
Guerrero-Ferreira, R. C., Hupfeld, M., Nazarov, S., Taylor, N. M. I., Shneider, M. M., Obbineni, J. M., … Leiman, P. G. (2019). Structure and transformation of bacteriophage A511 baseplate and tail upon infection of Listeria cells. EMBO Journal, 38(3), e99455 (20 pp.). https://doi.org/10.15252/embj.201899455
Reactions of fission products from a <sup>252</sup>Cf source with NO and mixtures of NO and CO in an inert gas
Gäggeler, H. W., Usoltsev, I., & Eichler, R. (2019). Reactions of fission products from a 252Cf source with NO and mixtures of NO and CO in an inert gas. Radiochimica Acta, 107(7), 555-560. https://doi.org/10.1515/ract-2018-3076
Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography
Górzny, M. Ł., Opara, N. L., Guzenko, V. A., Cadarso, V. J., Schift, H., Li, X. D., & Padeste, C. (2019). Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography. Micro and Nano Engineering, 3, 31-36. https://doi.org/10.1016/j.mne.2019.03.002