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  • (-) PSI Divisions = Biology and Chemistry BIO
  • (-) Publication Year = 2020 - 2020
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Combined application of albumin-binding [<sup>177</sup>Lu]Lu-PSMA-ALB-56 and fast-cleared PSMA inhibitors: optimization of the pharmacokinetics
Borgna, F., Deberle, L. M., Cohrs, S., Schibli, R., & Müller, C. (2020). Combined application of albumin-binding [177Lu]Lu-PSMA-ALB-56 and fast-cleared PSMA inhibitors: optimization of the pharmacokinetics. Molecular Pharmaceutics, 17(6), 2044-2053. https://doi.org/10.1021/acs.molpharmaceut.0c00199
Production and application of nanobodies for membrane protein structural biology
Brunner, J. D., & Schenck, S. (2020). Production and application of nanobodies for membrane protein structural biology. In C. Perez & T. Maier (Eds.), Methods in molecular biology: Vol. 2127. Expression, purification, and structural biology of membrane proteins. https://doi.org/10.1007/978-1-0716-0373-4_12
Structural basis for ion selectivity in TMEM175 K<sup>+</sup> channels
Brunner, J. D., Jakob, R. P., Schulze, T., Neldner, Y., Moroni, A., Thiel, G., … Schenck, S. (2020). Structural basis for ion selectivity in TMEM175 K+ channels. eLife, 9, e53683 (24 pp.). https://doi.org/10.7554/eLife.53683
Cryo-EM structure of the Hedgehog release protein Dispatched
Cannac, F., Qi, C., Falschlunger, J., Hausmann, G., Basler, K., & Korkhov, V. M. (2020). Cryo-EM structure of the Hedgehog release protein Dispatched. Science Advances, 6(16), eaay7928 (8 pp.). https://doi.org/10.1126/sciadv.aay7928
Separation and recovery of exotic radiolanthanides from irradiated tantalum targets for half-life measurements
Chiera, N. M., Talip, Z., Fankhauser, A., & Schumann, D. (2020). Separation and recovery of exotic radiolanthanides from irradiated tantalum targets for half-life measurements. PLoS One, 15(7), e0235711 (19 pp.). https://doi.org/10.1371/journal.pone.0235711
Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity
Deberle, L. M., Benešová, M., Umbricht, C. A., Borgna, F., Büchler, M., Zhernosekov, K., … Müller, C. (2020). Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity. Theranostics, 10(4), 1678-1693. https://doi.org/10.7150/thno.40482
The A/T/N model applied through imaging biomarkers in a memory clinic
Dodich, A., Mendes, A., Assal, F., Chicherio, C., Rakotomiaramanana, B., Andryszak, P., … Garibotto, V. (2020). The A/T/N model applied through imaging biomarkers in a memory clinic. European Journal of Nuclear Medicine and Molecular Imaging, 47(2), 247-255. https://doi.org/10.1007/s00259-019-04536-9
Determination of <sup>161</sup>Tb half-life by three measurement methods
Durán, M. T., Juget, F., Nedjadi, Y., Bochud, F., Grundler, P. V., Gracheva, N., … Bailat, C. (2020). Determination of 161Tb half-life by three measurement methods. Applied Radiation and Isotopes, 159, 109085 (9 pp.). https://doi.org/10.1016/j.apradiso.2020.109085
Structural model for differential cap maturation at growing microtubule ends
Estévez-Gallego, J., Josa-Prado, F., Ku, S., Buey, R. M., Balaguer, F. A., Prota, A. E., … Oliva, M. A. (2020). Structural model for differential cap maturation at growing microtubule ends. eLife, 9, e50155 (26 pp.). https://doi.org/10.7554/eLife.50155
Homodimerization of coronin A through the C-terminal coiled-coil domain is essential for multicellular differentiation of <em>Dictyostelium discoideum</em>
Fiedler, T., Fabrice, T. N., Studer, V., Vinet, A., Faltova, L., Kammerer, R. A., … Pieters, J. (2020). Homodimerization of coronin A through the C-terminal coiled-coil domain is essential for multicellular differentiation of Dictyostelium discoideum. FEBS Letters, 594(13), 2116-2127. https://doi.org/10.1002/1873-3468.13787
Radiation dosimetry of <sup>18</sup>F-AzaFol: a first in-human use of a folate receptor PET tracer
Gnesin, S., Müller, J., Burger, I. A., Meisel, A., Siano, M., Früh, M., … Schaefer, N. (2020). Radiation dosimetry of 18F-AzaFol: a first in-human use of a folate receptor PET tracer. EJNMMI Research, 10(1), 32 (12 pp.). https://doi.org/10.1186/s13550-020-00624-2
<sup>165</sup>Er: a new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets
Gracheva, N., Carzaniga, T. S., Schibli, R., Braccini, S., & van der Meulen, N. P. (2020). 165Er: a new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets. Applied Radiation and Isotopes, 159, 109079 (8 pp.). https://doi.org/10.1016/j.apradiso.2020.109079
Affinity purification of membrane proteins
Graeber, E., & Korkhov, V. M. (2020). Affinity purification of membrane proteins. In C. Perez & T. Maier (Eds.), Methods in molecular biology: Vol. 2127. Expression, purification, and structural biology of membrane proteins. https://doi.org/10.1007/978-1-0716-0373-4_9
Design of radiolabeled analogs of minigastrin by multiple amide-to-triazole substitutions
Grob, N. M., Schmid, S., Schibli, R., Behe, M., & Mindt, T. L. (2020). Design of radiolabeled analogs of minigastrin by multiple amide-to-triazole substitutions. Journal of Medicinal Chemistry, 63(9), 4496-4505. https://doi.org/10.1021/acs.jmedchem.9b01937
Triazolo-peptidomimetics: novel radiolabeled minigastrin analogs for improved tumor targeting
Grob, N. M., Häussinger, D., Deupi, X., Schibli, R., Behe, M., & Mindt, T. L. (2020). Triazolo-peptidomimetics: novel radiolabeled minigastrin analogs for improved tumor targeting. Journal of Medicinal Chemistry, 63(9), 4484-4495. https://doi.org/10.1021/acs.jmedchem.9b01936
Structural refinement of the tubulin ligand (+)-discodermolide to attenuate chemotherapy-mediated senescence
Guo, B., Rodriguez-Gabin, A., Prota, A. E., Mühlethaler, T., Zhang, N., Ye, K., … McDaid, H. M. (2020). Structural refinement of the tubulin ligand (+)-discodermolide to attenuate chemotherapy-mediated senescence. Molecular Pharmacology, 98(2), 156-167. https://doi.org/10.1124/mol.119.117457
A lathe system for micrometre-sized cylindrical sample preparation at room and cryogenic temperatures
Holler, M., Ihli, J., Tsai, E. H. R., Nudelman, F., Verezhak, M., van de Berg, W. D. J., & Shahmoradian, S. H. (2020). A lathe system for micrometre-sized cylindrical sample preparation at room and cryogenic temperatures. Journal of Synchrotron Radiation, 27(2), 472-476. https://doi.org/10.1107/S1600577519017028
Pharmaceutical-grade rigosertib is a microtubule-destabilizing agent
Jost, M., Chen, Y., Gilbert, L. A., Horlbeck, M. A., Krenning, L., Menchon, G., … Weissman, J. S. (2020). Pharmaceutical-grade rigosertib is a microtubule-destabilizing agent. Molecular Cell, 79(1), 191-198.e3. https://doi.org/10.1016/j.molcel.2020.06.008
Structure and function of adenylyl cyclases, key enzymes in cellular signaling
Khannpnavar, B., Mehta, V., Qi, C., & Korkhov, V. (2020). Structure and function of adenylyl cyclases, key enzymes in cellular signaling. Current Opinion in Structural Biology, 63, 34-41. https://doi.org/10.1016/j.sbi.2020.03.003
Holography and coherent diffraction imaging with low-(30-250 eV) and high-(80-300 keV) energy electrons: history, principles, and recent trends
Latychevskaia, T. (2020). Holography and coherent diffraction imaging with low-(30-250 eV) and high-(80-300 keV) energy electrons: history, principles, and recent trends. Materials, 13(14), 3089 (36 pp.). https://doi.org/10.3390/ma13143089