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Ultrafast structural changes direct the first molecular events of vision
Gruhl, T., Weinert, T., Rodrigues, M. J., Milne, C. J., Ortolani, G., Nass, K., … Panneels, V. (2023). Ultrafast structural changes direct the first molecular events of vision. Nature, 615, 939-944. https://doi.org/10.1038/s41586-023-05863-6
Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist
Isaikina, P., Tsai, C. J., Dietz, N., Pamula, F., Grahl, A., Goldie, K. N., … Grzesiek, S. (2021). Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist. Science Advances, 7(25), eabg8685 (11 pp.). https://doi.org/10.1126/sciadv.abg8685
Biochemical characterization of GPCR-G protein complex formation
Pamula, F., & Tsai, C. J. (2021). Biochemical characterization of GPCR-G protein complex formation. In I. Schmidt-Krey & J. C. Gumbart (Eds.), Methods in molecular biology: Vol. 2302. Structure and function of membrane proteins (pp. 37-48). https://doi.org/10.1007/978-1-0716-1394-8_3
Strategic screening and characterization of the visual GPCR-mini-G protein signaling complex for successful crystallization
Pamula, F., Mühle, J., Blanc, A., Nehmé, R., Edwards, P. C., Tate, C. G., & Tsai, C. J. (2020). Strategic screening and characterization of the visual GPCR-mini-G protein signaling complex for successful crystallization. Journal of Visualized Experiments, 2020(157), e60747 (10 pp.). https://doi.org/10.3791/60747
Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit
Tsai, C. J., Marino, J., Adaixo, R., Pamula, F., Muehle, J., Maeda, S., … Schertler, G. (2019). Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit. eLife, 8, e46041 (19 pp.). https://doi.org/10.7554/eLife.46041
Crystal structure of rhodopsin in complex with a mini-G<sub>o</sub> sheds light on the principles of G protein selectivity
Tsai, C. J., Pamula, F., Nehmé, R., Mühle, J., Weinert, T., Flock, T., … Schertler, G. F. X. (2018). Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity. Science Advances, 4(9), aat7052 (9 pp.). https://doi.org/10.1126/sciadv.aat7052