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Deep learning applications in protein crystallography
Matinyan, S., Filipcik, P., & Abrahams, J. P. (2024). Deep learning applications in protein crystallography. Acta Crystallographica Section A: Foundations and Advances, 80(1), 1-17. https://doi.org/10.1107/S2053273323009300
DiffraGAN: a conditional generative adversarial network for phasing single molecule diffraction data to atomic resolution
Matinyan, S., Filipcik, P., van Genderen, E., & Abrahams, J. P. (2024). DiffraGAN: a conditional generative adversarial network for phasing single molecule diffraction data to atomic resolution. Frontiers in Molecular Biosciences, 11, 1386963 (11 pp.). https://doi.org/10.3389/fmolb.2024.1386963
Electrostatic interference control of a high-energy coherent electron beam using a three-element Boersch phase shifter
Thakkar, P., Guzenko, V. A., Lu, P., Dunin-Borkowski, R. E., Abahams, J. P., & Tsujino, S. (2024). Electrostatic interference control of a high-energy coherent electron beam using a three-element Boersch phase shifter. Japanese Journal of Applied Physics. https://doi.org/10.35848/1347-4065/ad7341
Machine learning for classifying narrow-beam electron diffraction data
Matinyan, S., Demir, B., Filipcik, P., Abrahams, J. P., & van Genderen, E. (2023). Machine learning for classifying narrow-beam electron diffraction data. Acta Crystallographica Section A: Foundations and Advances, 79, 360-368. https://doi.org/10.1107/S2053273323004680
TERSE/PROLIX (TRPX) - a new algorithm for fast and lossless compression and decompression of diffraction and cryo-EM data
Matinyan, S., & Abrahams, J. P. (2023). TERSE/PROLIX (TRPX) - a new algorithm for fast and lossless compression and decompression of diffraction and cryo-EM data. Acta Crystallographica Section A: Foundations and Advances, 79(6), 536-541. https://doi.org/10.1107/S205327332300760X
Cryptosporulation in <em>Kurthia</em> spp. forces a rethinking of asporogenesis in Firmicutes
Fatton, M., Filippidou, S., Junier, T., Cailleau, G., Berge, M., Poppleton, D., … Junier, P. (2022). Cryptosporulation in Kurthia spp. forces a rethinking of asporogenesis in Firmicutes. Environmental Microbiology, 24(12), 6320-6335. https://doi.org/10.1111/1462-2920.16145
Electron detection with CdTe and GaAs sensors using the charge integrating hybrid pixel detector JUNGFRAU
Fröjdh, E., Abrahams, J. P., Andrä, M., Barten, R., Bergamaschi, A., Brückner, M., … Zhang, J. (2022). Electron detection with CdTe and GaAs sensors using the charge integrating hybrid pixel detector JUNGFRAU. Journal of Instrumentation, 17, C01020 (12 pp.). https://doi.org/10.1088/1748-0221/17/01/C01020
Catalytic cycling of human mitochondrial Lon protease
Mohammed, I., Schmitz, K. A., Schenck, N., Balasopoulos, D., Topitsch, A., Maier, T., & Abrahams, J. P. (2022). Catalytic cycling of human mitochondrial Lon protease. Structure, 30(9), 1254-1268. https://doi.org/10.1016/j.str.2022.06.006
Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals
Blum, T. B., Housset, D., Clabbers, M. T. B., van Genderen, E., Bacia-Verloop, M., Zander, U., … Abrahams, J. P. (2021). Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals. Acta Crystallographica Section D: Structural Biology, 77, 75-85. https://doi.org/10.1107/S2059798320014540
Voltage-controlled three-electron-beam interference by a three-element Boersch phase shifter with top and bottom shielding electrodes
Thakkar, P., Guzenko, V. A., Lu, P. H., Dunin-Borkowski, R. E., Abrahams, J. P., & Tsujino, S. (2021). Voltage-controlled three-electron-beam interference by a three-element Boersch phase shifter with top and bottom shielding electrodes. In S. Purcell & J. P. Mazellier (Eds.), International conference on vacuum nanoelectronics (IVNC). 2021 34th international vacuum nanoelectronics conference (IVNC) (p. 21299961 (2 pp.). https://doi.org/10.1109/IVNC52431.2021.9600711
Cryo-electron microscopy imaging of Alzheimer's amyloid-beta 42 oligomer displayed on a functionally and structurally relevant scaffold
Wu, J., Blum, T. B., Farrell, D. P., DiMaio, F., Abrahams, J. P., & Luo, J. (2021). Cryo-electron microscopy imaging of Alzheimer's amyloid-beta 42 oligomer displayed on a functionally and structurally relevant scaffold. Angewandte Chemie International Edition, 60(34), 18680-18687. https://doi.org/10.1002/anie.202104497
Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in &lt;em&gt;Streptomyces&lt;/em&gt;
Xiao, X., Willemse, J., Voskamp, P., Li, X., Prota, A. E., Lamers, M., … van Wezel, G. P. (2021). Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in Streptomyces. Open Biology, 11(2), 200409 (14 pp.). https://doi.org/10.1098/rsob.200409
A lipocalin mediates unidirectional heme biomineralization in malaria parasites
Matz, J. M., Drepper, B., Blum, T. B., van Genderen, E., Burrell, A., Martin, P., … Blackman, M. J. (2020). A lipocalin mediates unidirectional heme biomineralization in malaria parasites. Proceedings of the National Academy of Sciences of the United States of America PNAS, 117(28), 16546-16556. https://doi.org/10.1073/pnas.2001153117
Shape-shifting peptide nanomaterials: surface asymmetry enables pH-dependent formation and interconversion of collagen tubes and sheets
Merg, A. D., Touponse, G., van Genderen, E., Blum, T. B., Zuo, X., Bazrafshan, A., … Conticello, V. P. (2020). Shape-shifting peptide nanomaterials: surface asymmetry enables pH-dependent formation and interconversion of collagen tubes and sheets. Journal of the American Chemical Society, 142(47), 19956-19968. https://doi.org/10.1021/jacs.0c08174
Demonstration of the voltage-controlled three-beam interference of high-energy coherent electron beam
Thakkar, P., Guzenko, V., Abrahams, J. P., Tsujino, S., Lu, P. H., & Dunin-Borkowski, R. E. (2020). Demonstration of the voltage-controlled three-beam interference of high-energy coherent electron beam. In 2020 33rd international vacuum nanoelectronics conference (IVNC). 33rd international vacuum nanoelectronics conference (IVNC) July 6-7, 2020 (p. 9203341 (2 pp.). https://doi.org/10.1109/IVNC49440.2020.9203341
Fabrication of low aspect ratio three-element Boersch phase shifters for voltage-controlled three electron beam interference
Thakkar, P., Guzenko, V. A., Lu, P. H., Dunin-Borkowski, R. E., Abrahams, J. P., & Tsujino, S. (2020). Fabrication of low aspect ratio three-element Boersch phase shifters for voltage-controlled three electron beam interference. Journal of Applied Physics, 128(13), 134502 (13 pp.). https://doi.org/10.1063/5.0020383
Functional and structural insights into a novel promiscuous ketoreductase of the lugdunomycin biosynthetic pathway
Xiao, X., Elsayed, S. S., Wu, C., van der Heul, H. U., Metsä-Ketelä, M., Du, C., … van Wezel, G. P. (2020). Functional and structural insights into a novel promiscuous ketoreductase of the lugdunomycin biosynthetic pathway. ACS Chemical Biology, 15(9), 2529-2538. https://doi.org/10.1021/acschembio.0c00564
Sub-pixel electron detection using a convolutional neural network
van Schayck, J. P., van Genderen, E., Maddox, E., Roussel, L., Boulanger, H., Fröjdh, E., … Ravelli, R. B. G. (2020). Sub-pixel electron detection using a convolutional neural network. Ultramicroscopy, 218, 113091 (10 pp.). https://doi.org/10.1016/j.ultramic.2020.113091
The wild-type flagellar filament of the Firmicute &lt;em&gt;Kurthia &lt;/em&gt;at 2.8 Å resolution &lt;em&gt;in vivo&lt;/em&gt;
Blum, T. B., Filippidou, S., Fatton, M., Junier, P., & Abrahams, J. P. (2019). The wild-type flagellar filament of the Firmicute Kurthia at 2.8 Å resolution in vivo. Scientific Reports, 9(1), 14948 (8 pp.). https://doi.org/10.1038/s41598-019-51440-1
Reducing dynamical electron scattering reveals hydrogen atoms
Clabbers, M. T. B., Gruene, T., van Genderen, E., & Abrahams, J. P. (2019). Reducing dynamical electron scattering reveals hydrogen atoms. Acta Crystallographica Section A: Foundations and Advances, 75(1), 82-93. https://doi.org/10.1107/S2053273318013918