| Production and biochemical characterization of dimeric recombinant gremlin-1
Mitola, S., Ravelli, C., Corsini, M., Gianoncelli, A., Galvagni, F., Ballmer-Hofer, K., … Grillo, E. (2022). Production and biochemical characterization of dimeric recombinant gremlin-1. International Journal of Molecular Sciences, 23(3), 1151 (10 pp.). https://doi.org/10.3390/ijms23031151 |
| ScFvs as allosteric inhibitors of VEGFR-2: novel tools to harness VEGF signaling
Ballmer-Hofer, K., Hyde, C. A. C., Schleier, T., & Avramovic, D. (2018). ScFvs as allosteric inhibitors of VEGFR-2: novel tools to harness VEGF signaling. International Journal of Molecular Sciences, 19(5), 1334 (15 pp.). https://doi.org/10.3390/ijms19051334 |
| Vascular Endothelial Growth Factor, from basic research to clinical applications
Ballmer-Hofer, K. (2018). Vascular Endothelial Growth Factor, from basic research to clinical applications. International Journal of Molecular Sciences, 19(12), 3750 (5 pp.). https://doi.org/10.3390/ijms19123750 |
| VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis
Beazley-Long, N., Moss, C. E., Ashby, W. R., Bestall, S. M., Almahasneh, F., Durrant, A. M., … Donaldson, L. F. (2018). VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis. Brain, Behavior, and Immunity, 74, 49-67. https://doi.org/10.1016/j.bbi.2018.03.012 |
| Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling
Thieltges, K. M., Avramovic, D., Piscitelli, C. L., Markovic-Mueller, S., Binz, H. K., & Ballmer-Hofer, K. (2018). Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling. Angiogenesis, 21(3), 533-543. https://doi.org/10.1007/s10456-018-9606-9 |
| Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain
Ved, N., Da Vitoria Lobo, M. E., Bestall, S. M., Vidueira, C. L., Beazley-Long, N., Ballmer-Hofer, K., … Hulse, R. P. (2018). Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain. Journal of Physiology, 596(16), 3675-3693. https://doi.org/10.1113/JP275067 |
| Structure of the full-length VEGFR-1 extracellular domain in complex with VEGF-A
Markovic-Mueller, S., Stuttfeld, E., Asthana, M., Weinert, T., Bliven, S., Goldie, K. N., … Ballmer-Hofer, K. (2017). Structure of the full-length VEGFR-1 extracellular domain in complex with VEGF-A. Structure, 25(2), 341-352. https://doi.org/10.1016/j.str.2016.12.012 |
| Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist
Grillo, E., Ravelli, C., Corsini, M., Ballmer-Hofer, K., Zammataro, L., Oreste, P., … Mitola, S. (2016). Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist. Oncotarget, 7(23), 35353-35368. https://doi.org/10.18632/oncotarget.9286 |
| VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
Li, X., Padhan, N., Sjöström, E. O., Roche, F. P., Testini, C., Honkura, N., … Claesson-Welsh, L. (2016). VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread. Nature Communications, 7, 11017 (16 pp.). https://doi.org/10.1038/ncomms11017 |
| Highly efficient baculovirus-mediated multigene delivery in primary cells
Mansouri, M., Bellon-Echeverria, I., Rizk, A., Ehsaei, Z., Cianciolo Cosentino, C., Silva, C. S., … Berger, P. (2016). Highly efficient baculovirus-mediated multigene delivery in primary cells. Nature Communications, 7, 11529 (13 pp.). https://doi.org/10.1038/ncomms11529 |
| VEGFR-2 conformational switch in response to ligand binding
Sarabipour, S., Ballmer-Hofer, K., & Hristova, K. (2016). VEGFR-2 conformational switch in response to ligand binding. eLife, 5, e13876 (23 pp.). https://doi.org/10.7554/eLife.13876 |
| Vascular endothelial growth factor-A<sub>165</sub>b prevents diabetic neuropathic pain and sensory neuronal degeneration
Hulse, R. P., Beazley-Long, N., Ved, N., Bestall, S. M., Riaz, H., Singhal, P., … Donaldson, L. F. (2015). Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration. Clinical Science, 129(8), 741-756. https://doi.org/10.1042/CS20150124 |
| Vascular endothelial growth factor-A<sub>165</sub>b is protective and restores endothelial glycocalyx in diabetic nephropathy
Oltean, S., Qiu, Y., Ferguson, J. K., Stevens, M., Neal, C., Russell, A., … Salmon, A. H. J. (2015). Vascular endothelial growth factor-A165b is protective and restores endothelial glycocalyx in diabetic nephropathy. Journal of the American Society of Nephrology, 26(8), 1889-1904. https://doi.org/10.1681/ASN.2014040350 |
| Subcellular object quantification with Squassh3C and SquasshAnalyst
Rizk, A., Mansouri, M., Ballmer-Hofer, K., & Berger, P. (2015). Subcellular object quantification with Squassh3C and SquasshAnalyst. BioTechniques, 59(5), 309-311. https://doi.org/10.2144/000114352 |
| Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia
Hulse, R. P., Beazley-Long, N., Hua, J., Kennedy, H., Prager, J., Bevan, H., … Donaldson, L. F. (2014). Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia. Neurobiology of Disease, 71, 245-259. https://doi.org/10.1016/j.nbd.2014.08.012 |
| Functional and structural characterization of the kinase insert and the carboxy terminal domain in VEGF receptor 2 activation
Manni, S., Kisko, K., Schleier, T., Missimer, J., & Ballmer-Hofer, K. (2014). Functional and structural characterization of the kinase insert and the carboxy terminal domain in VEGF receptor 2 activation. FASEB Journal, 28(11), 4914-4923. https://doi.org/10.1096/fj.14-256206 |
| Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Manni, S., Mineev, K. S., Usmanova, D., Lyukmanova, E. N., Shulepko, M. A., Kirpichnikov, M. P., … Ballmer-Hofer, K. (2014). Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation. Structure, 22(8), 1077-1089. https://doi.org/10.1016/j.str.2014.05.010 |
| High-level secretion of recombinant full-length streptavidin in <em>Pichia pastoris </em>and its application to enantioselective catalysis
Nogueira, E. S., Schleier, T., Dürrenberger, M., Ballmer-Hofer, K., Ward, T. R., & Jaussi, R. (2014). High-level secretion of recombinant full-length streptavidin in Pichia pastoris and its application to enantioselective catalysis. Protein Expression and Purification, 93, 54-62. https://doi.org/10.1016/j.pep.2013.10.015 |
| Cell lines expressing recombinant transmembrane domain-activated receptor kinases as tools for drug discovery
Weber, H., Müller, D., Müller, M., Ortiz, A., Birkle, M., Umber, S., … Graeser, R. (2014). Cell lines expressing recombinant transmembrane domain-activated receptor kinases as tools for drug discovery. Journal of Biomolecular Screening, 19(10), 1350-1361. https://doi.org/10.1177/1087057114552414 |
| Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation
Leppänen, V. M., Tvorogov, D., Kisko, K., Prota, A. E., Jeltsch, M., Anisimov, A., … Alitalo, K. (2013). Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation. Proceedings of the National Academy of Sciences of the United States of America PNAS, 110(32), 12960-12965. https://doi.org/10.1073/pnas.1301415110 |
