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Design and evaluation of novel albumin-binding folate radioconjugates: systematic approach of varying the linker entities
Benešová, M., Guzik, P., Deberle, L. M., Busslinger, S. D., Landolt, T., Schibli, R., & Müller, C. (2022). Design and evaluation of novel albumin-binding folate radioconjugates: systematic approach of varying the linker entities. Molecular Pharmaceutics, 19, 963-973. https://doi.org/10.1021/acs.molpharmaceut.1c00932
Novel synthetic strategies enable the efficient development of folate conjugates for cancer radiotheranostics
Deberle, L. M., Benešová, M., Becker, A. E., Ratz, M., Guzik, P., Schibli, R., & Müller, C. (2021). Novel synthetic strategies enable the efficient development of folate conjugates for cancer radiotheranostics. Bioconjugate Chemistry, 32(8), 1617-1628. https://doi.org/10.1021/acs.bioconjchem.1c00198
Identification of a PET radiotracer for imaging of the folate receptor-α: a potential tool to select patients for targeted tumor therapy
Guzik, P., Fang, H. Y., Deberle, L. M., Benešová, M., Cohrs, S., Boss, S. D., … Müller, C. (2021). Identification of a PET radiotracer for imaging of the folate receptor-α: a potential tool to select patients for targeted tumor therapy. Journal of Nuclear Medicine, 62(10), 1475-1481. https://doi.org/10.2967/jnumed.120.255760
Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates - new perspectives for folate receptor-targeted radionuclide therapy
Guzik, P., Benešová, M., Ratz, M., Monné Rodríguez, J. M., Deberle, L. M., Schibli, R., & Müller, C. (2021). Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates - new perspectives for folate receptor-targeted radionuclide therapy. European Journal of Nuclear Medicine and Molecular Imaging, 48, 972-983. https://doi.org/10.1007/s00259-020-04980-y
Biodistribution and dosimetry of a single dose of albumin-binding ligand [<sup>177</sup>Lu]Lu-PSMA-ALB-56 in patients with mCRPC
Kramer, V., Fernández, R., Lehnert, W., Jiménez-Franco, L. D., Soza-Ried, C., Eppard, E., … Müller, C. (2021). Biodistribution and dosimetry of a single dose of albumin-binding ligand [177Lu]Lu-PSMA-ALB-56 in patients with mCRPC. European Journal of Nuclear Medicine and Molecular Imaging, 48, 893-903. https://doi.org/10.1007/s00259-020-05022-3
Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity
Deberle, L. M., Benešová, M., Umbricht, C. A., Borgna, F., Büchler, M., Zhernosekov, K., … Müller, C. (2020). Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity. Theranostics, 10(4), 1678-1693. https://doi.org/10.7150/thno.40482
Internal radiation dosimetry of a &lt;sup&gt;152&lt;/sup&gt;Tb-labeled antibody in tumor-bearing mice
Cicone, F., Gnesin, S., Denoël, T., Stora, T., van der Meulen, N. P., Müller, C., … Prior, J. O. (2019). Internal radiation dosimetry of a 152Tb-labeled antibody in tumor-bearing mice. EJNMMI Research, 9, 53 (10 pp.). https://doi.org/10.1186/s13550-019-0524-7
Preclinical investigations and first-in-human application of &lt;sup&gt;152&lt;/sup&gt;Tb-PSMA-617 for PET/CT imaging of prostate cancer
Müller, C., Singh, A., Umbricht, C. A., Kulkarni, H. R., Johnston, K., Benešová, M., … Baum, R. P. (2019). Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer. EJNMMI Research, 9(1), 68 (10 pp.). https://doi.org/10.1186/s13550-019-0538-1
New &lt;sup&gt;55&lt;/sup&gt;Co-labeled albumin-binding folate derivatives as potential PET agents for folate receptor imaging
Radford, L. L., Fernandez, S., Beacham, R., Sayed, R. E., Farkas, R., Benešová, M., … Lapi, S. E. (2019). New 55Co-labeled albumin-binding folate derivatives as potential PET agents for folate receptor imaging. Pharmaceuticals, 12(4), 166 (12 pp.). https://doi.org/10.3390/ph12040166
&lt;sup&gt;18&lt;/sup&gt;F-AzaFol for detection of folate receptor-β positive macrophages in experimental interstitial lung disease - a proof-of-concept study
Schniering, J., Benešová, M., Brunner, M., Haller, S., Cohrs, S., Frauenfelder, T., … Maurer, B. (2019). 18F-AzaFol for detection of folate receptor-β positive macrophages in experimental interstitial lung disease - a proof-of-concept study. Frontiers in Immunology, 10, 2724 (15 pp.). https://doi.org/10.3389/fimmu.2019.02724
Implementation of a new separation method to produce qualitatively improved &lt;sup&gt;64&lt;/sup&gt;Cu
van der Meulen, N. P., Hasler, R., Blanc, A., Farkas, R., Benešová, M., Talip, Z., … Schibli, R. (2019). Implementation of a new separation method to produce qualitatively improved 64Cu. Journal of Labelled Compounds and Radiopharmaceuticals, 62(8), 460-470. https://doi.org/10.1002/jlcr.3730
Albumin-binding PSMA ligands: optimization of the tissue distribution profile
Benešová, M., Umbricht, C. A., Schibli, R., & Müller, C. (2018). Albumin-binding PSMA ligands: optimization of the tissue distribution profile. Molecular Pharmaceutics, 15(3), 934-946. https://doi.org/10.1021/acs.molpharmaceut.7b00877
In vivo labeling of plasma proteins for imaging of enhanced vascular permeability in the lungs
Schniering, J., Borgna, F., Siwowska, K., Benešová, M., Cohrs, S., Hasler, R., … Müller, C. (2018). In vivo labeling of plasma proteins for imaging of enhanced vascular permeability in the lungs. Molecular Pharmaceutics, 15(11), 4995-5004. https://doi.org/10.1021/acs.molpharmaceut.8b00606
Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2
Schniering, J., Benešová, M., Brunner, M., Haller, S., Cohrs, S., Frauenfelder, T., … Maurer, B. (2018). Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2. Annals of the Rheumatic Diseases, 78(2), 218-227. https://doi.org/10.1136/annrheumdis-2018-214322
Design and preclinical evaluation of an albumin-binding PSMA ligand for &lt;sup&gt;64&lt;/sup&gt;Cu-based PET imaging
Umbricht, C. A., Benešová, M., Hasler, R., Schibli, R., van der Meulen, N. P., & Müller, C. (2018). Design and preclinical evaluation of an albumin-binding PSMA ligand for 64Cu-based PET imaging. Molecular Pharmaceutics, 15(12), 5556-5564. https://doi.org/10.1021/acs.molpharmaceut.8b00712
Preclinical development of novel PSMA-targeting radioligands: modulation of albumin-binding properties to improve prostate cancer therapy
Umbricht, C. A., Benešová, M., Schibli, R., & Müller, C. (2018). Preclinical development of novel PSMA-targeting radioligands: modulation of albumin-binding properties to improve prostate cancer therapy. Molecular Pharmaceutics, 15(6), 2297-2306. https://doi.org/10.1021/acs.molpharmaceut.8b00152
Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with &lt;sup&gt;152&lt;/sup&gt;Tb-DOTATOC
Baum, R. P., Singh, A., Benešová, M., Vermeulen, C., Gnesin, S., Köster, U., … Müller, C. (2017). Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC. Dalton Transactions, 46(42), 14638-14646. https://doi.org/10.1039/c7dt01936j
&lt;sup&gt;47&lt;/sup&gt;Sc as useful β&lt;sup&gt;–&lt;/sup&gt;-emitter for the radiotheragnostic paradigm: a comparative study of feasible production routes
Domnanich, K. A., Müller, C., Benešová, M., Dressler, R., Haller, S., Köster, U., … van der Meulen, N. P. (2017). 47Sc as useful β-emitter for the radiotheragnostic paradigm: a comparative study of feasible production routes. EJNMMI Radiopharmacy and Chemistry, 2, 5 (17 pp.). https://doi.org/10.1186/s41181-017-0024-x
Glu-ureido-based inhibitors of prostate-specific membrane antigen: lessons learned during the development of a novel class of low-molecular-weight theranostic radiotracers
Kopka, K., Benešová, M., Bařinka, C., Haberkorn, U., & Babich, J. (2017). Glu-ureido-based inhibitors of prostate-specific membrane antigen: lessons learned during the development of a novel class of low-molecular-weight theranostic radiotracers. Journal of Nuclear Medicine, 58(Suppl. 2), 17S-26S. https://doi.org/10.2967/jnumed.116.186775
Synthesis, radiolabeling, and characterization of plasma protein-binding ligands: potential tools for modulation of the pharmacokinetic properties of (radio)pharmaceuticals
Müller, C., Farkas, R., Borgna, F., Schmid, R. M., Benešová, M., & Schibli, R. (2017). Synthesis, radiolabeling, and characterization of plasma protein-binding ligands: potential tools for modulation of the pharmacokinetic properties of (radio)pharmaceuticals. Bioconjugate Chemistry, 28(9), 2372-2383. https://doi.org/10.1021/acs.bioconjchem.7b00378