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Terbium-149 production: a focus on yield and quality improvement towards preclinical application
Favaretto, C., Grundler, P. V., Talip, Z., Köster, U., Johnston, K., Busslinger, S. D., … van der Meulen, N. P. (2024). Terbium-149 production: a focus on yield and quality improvement towards preclinical application. Scientific Reports, 14(1), 3284 (12 pp.). https://doi.org/10.1038/s41598-024-53610-2
First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([<sup>161</sup>Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum
Fricke, J., Westerbergh, F., McDougall, L., Favaretto, C., Christ, E., Nicolas, G. P., … Wild, D. (2024). First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum. European Journal of Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s00259-024-06641-w
Preclinical evaluation of gastrin-releasing peptide receptor antagonists labeled with <sup>161</sup>Tb and <sup>177</sup>Lu: a comparative study
Holzleitner, N., Cwojdzinski, T., Beck, R., Urtz-Urban, N., Hillhouse, C. C., Grundler, P. V., … Günther, T. (2024). Preclinical evaluation of gastrin-releasing peptide receptor antagonists labeled with 161Tb and 177Lu: a comparative study. Journal of Nuclear Medicine, 65(3), 481-484. https://doi.org/10.2967/jnumed.123.266233
A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides
Beyer, D., Vaccarin, C., Deupi, X., Mapanao, A. K., Cohrs, S., Sozzi-Guo, F., … Müller, C. (2023). A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides. EJNMMI Research, 13(1), 32 (14 pp.). https://doi.org/10.1186/s13550-023-00979-2
Cross-section measurement of thulium radioisotopes with an 18 MeV medical PET cyclotron for an optimized <sup>165</sup>Er production
Dellepiane, G., Casolaro, P., Favaretto, C., Gottstein, A., Grundler, P. V., Mateu, I., … Braccini, S. (2023). Cross-section measurement of thulium radioisotopes with an 18 MeV medical PET cyclotron for an optimized 165Er production. Applied Radiation and Isotopes, 200, 110954 (11 pp.). https://doi.org/10.1016/j.apradiso.2023.110954
<sup>161</sup>Tb-DOTATOC production using a fully automated disposable cassette system: a first step toward the introduction of <sup>161</sup>Tb into the clinic
Favaretto, C., Grundler, P. V., Talip, Z., Landolt, S., Sepini, L., Köster, U., … van der Meulen, N. P. (2023). 161Tb-DOTATOC production using a fully automated disposable cassette system: a first step toward the introduction of 161Tb into the clinic. Journal of Nuclear Medicine, 64(7), 1138-1144. https://doi.org/10.2967/jnumed.122.265268
Synthesis and preclinical evaluation of radiolabeled [<sup>103</sup>Ru]BOLD-100
Happl, B., Brandt, M., Balber, T., Benčurová, K., Talip, Z., Voegele, A., … Mindt, T. L. (2023). Synthesis and preclinical evaluation of radiolabeled [103Ru]BOLD-100. Pharmaceutics, 15(11), 2626 (11 pp.). https://doi.org/10.3390/pharmaceutics15112626
Activity measurement of <sup>44</sup>Sc and calibration of activity measurement instruments on production sites and clinics
Juget, F., Durán, T., Nedjadi, Y., Talip, Z., Grundler, P. V., Favaretto, C., … van der Meulen, N. P. (2023). Activity measurement of 44Sc and calibration of activity measurement instruments on production sites and clinics. Molecules, 28(3), 1345 (10 pp.). https://doi.org/10.3390/molecules28031345
Opportunities and potential challenges of using terbium-161 for targeted radionuclide therapy in clinics
Müller, C., van der Meulen, N. P., & Schibli, R. (2023). Opportunities and potential challenges of using terbium-161 for targeted radionuclide therapy in clinics. European Journal of Nuclear Medicine and Molecular Imaging, 50, 3181-3184. https://doi.org/10.1007/s00259-023-06316-y
Study of thulium-167 cyclotron production: a potential medically-relevant radionuclide
Renaldin, E., Dellepiane, G., Braccini, S., Sommerhalder, A., Zhang, H., van der Meulen, N. P., … Talip, Z. (2023). Study of thulium-167 cyclotron production: a potential medically-relevant radionuclide. Frontiers in Chemistry, 11, 1288588 (14 pp.). https://doi.org/10.3389/fchem.2023.1288588
Albumin-binding and conventional PSMA ligands in combination with <sup>161</sup>Tb: biodistribution, dosimetry, and preclinical therapy
Tschan, V. J., Busslinger, S. D., Bernhardt, P., Grundler, P. V., Zeevaart, J. R., Köster, U., … Müller, C. (2023). Albumin-binding and conventional PSMA ligands in combination with 161Tb: biodistribution, dosimetry, and preclinical therapy. Journal of Nuclear Medicine, 64(10), 1625-1631. https://doi.org/10.2967/jnumed.123.265524
Combination of terbium-161 with somatostatin receptor antagonists - a potential paradigm shift for the treatment of neuroendocrine neoplasms
Borgna, F., Haller, S., Monné Rodriguez, J. M., Ginj, M., Grundler, P. V., Zeevaart, J. R., … Müller, C. (2022). Combination of terbium-161 with somatostatin receptor antagonists - a potential paradigm shift for the treatment of neuroendocrine neoplasms. European Journal of Nuclear Medicine and Molecular Imaging, 49, 1113-1126. https://doi.org/10.1007/s00259-021-05564-0
Optimization of <sup>68</sup>Ga production at an 18 MeV medical cyclotron with solid targets by means of cross-section measurement of <sup>66</sup>Ga, <sup>67</sup>Ga and <sup>68</sup>Ga
Braccini, S., Carzaniga, T. S., Dellepiane, G., Grundler, P. V., Scampoli, P., van der Meulen, N. P., & Wüthrich, D. (2022). Optimization of 68Ga production at an 18 MeV medical cyclotron with solid targets by means of cross-section measurement of 66Ga, 67Ga and 68Ga. Applied Radiation and Isotopes, 186, 110252 (9 pp.). https://doi.org/10.1016/j.apradiso.2022.110252
Cross section measurement of terbium radioisotopes for an optimized <sup>155</sup>Tb production with an 18 MeV medical PET cyclotron
Dellepiane, G., Casolaro, P., Favaretto, C., Grundler, P. V., Mateu, I., Scampoli, P., … Braccini, S. (2022). Cross section measurement of terbium radioisotopes for an optimized 155Tb production with an 18 MeV medical PET cyclotron. Applied Radiation and Isotopes, 184, 110175 (14 pp.). https://doi.org/10.1016/j.apradiso.2022.110175
Half-life measurement of <sup>44</sup>Sc and <sup>44m</sup>Sc
Durán, M. T., Juget, F., Nedjadi, Y., Bailat, C., Grundler, P. V., Talip, Z., … Braccini, S. (2022). Half-life measurement of 44Sc and 44mSc. Applied Radiation and Isotopes, 190, 110507 (10 pp.). https://doi.org/10.1016/j.apradiso.2022.110507
IMPACT conceptual design report
Eichler, R., Kiselev, D., Koschik, A., Knecht, A., van der Meulen, N., Scheibl, R., … Züllig, J. (2022). IMPACT conceptual design report. (PSI Bericht, Report No.: 22-01). Paul Scherrer Institut.
Active bone marrow S-values for the low-energy electron emitter terbium-161 compared to S-values for lutetium-177 and yttrium-90
Hemmingsson, J., Svensson, J., van der Meulen, N. P., Müller, C., & Bernhardt, P. (2022). Active bone marrow S-values for the low-energy electron emitter terbium-161 compared to S-values for lutetium-177 and yttrium-90. EJNMMI Physics, 9(1), 65 (13 pp.). https://doi.org/10.1186/s40658-022-00495-7
Precise activity measurements of medical radionuclides using an ionization chamber: a case study with Terbium-161
Juget, F., Talip, Z., Nedjadi, Y., Durán, M. T., Grundler, P. V., Zeevaart, J. R., … Bailat, C. (2022). Precise activity measurements of medical radionuclides using an ionization chamber: a case study with Terbium-161. EJNMMI Physics, 9(1), 19 (18 pp.). https://doi.org/10.1186/s40658-022-00448-0
Chelation of theranostic copper radioisotopes with S-rich macrocycles: from radiolabelling of copper-64 to in vivo investigation
Tosato, M., Verona, M., Favaretto, C., Pometti, M., Zanoni, G., Scopelliti, F., … Asti, M. (2022). Chelation of theranostic copper radioisotopes with S-rich macrocycles: from radiolabelling of copper-64 to in vivo investigation. Molecules, 27(13), 4158 (19 pp.). https://doi.org/10.3390/molecules27134158
Highlight selection of radiochemistry and radiopharmacy developments by editorial board
Alves, F., Antunes, I. F., Cazzola, E., Cleeren, F., Cornelissen, B., Denkova, A., … Taddei, C. (2021). Highlight selection of radiochemistry and radiopharmacy developments by editorial board. EJNMMI Radiopharmacy and Chemistry, 6(1), 31 (16 pp.). https://doi.org/10.1186/s41181-021-00146-9
 

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