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Poly(methyl methacrylate)-based nanofluidic device for rapid and multiplexed serological antibody detection of SARS-CoV-2
Mortelmans, T., Kazazis, D., Padeste, C., Berger, P., Li, X., & Ekinci, Y. (2022). Poly(methyl methacrylate)-based nanofluidic device for rapid and multiplexed serological antibody detection of SARS-CoV-2. ACS Applied Nano Materials, 5(1), 517-526. https://doi.org/10.1021/acsanm.1c03309
WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms
De Leo, M. G., Berger, P., & Mayer, A. (2021). WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms. Autophagy, 17(11), 3644-3670. https://doi.org/10.1080/15548627.2021.1886830
Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis
Nitzsche, A., Pietilä, R., Love, D. T., Testini, C., Ninchoji, T., Smith, R. O., … Hellström, M. (2021). Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis. EMBO Reports, 22(2), e5021 (16 pp.). https://doi.org/10.15252/embr.202050218
Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone
Romantini, N., Alam, S., Dobitz, S., Spillmann, M., De Foresta, M., Schibli, R., … Berger, P. (2021). Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone. Proceedings of the National Academy of Sciences of the United States of America PNAS, 118(48), e2108776118 (8 pp.). https://doi.org/10.1073/pnas.2108776118
Distance-dependent cellular uptake of oligoproline-based homobivalent ligands targeting GPCRs - an experimental and computational analysis
Dobitz, S., Wilhelm, P., Romantini, N., De Foresta, M., Walther, C., Ritler, A., … Wennemers, H. (2020). Distance-dependent cellular uptake of oligoproline-based homobivalent ligands targeting GPCRs - an experimental and computational analysis. Bioconjugate Chemistry, 31(10), 2431-2438. https://doi.org/10.1021/acs.bioconjchem.0c00484
Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [<sup>177</sup>Lu]Lu-PP-F11N
Grzmil, M., Qin, Y., Schleuniger, C., Frank, S., Imobersteg, S., Blanc, A., … Behe, M. (2020). Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [177Lu]Lu-PP-F11N. Theranostics, 10(24), 10861-10873. https://doi.org/10.7150/thno.45440
New insights into arrestin recruitment to GPCRs
Spillmann, M., Thurner, L., Romantini, N., Zimmermann, M., Meger, B., Behe, M., … Berger, P. (2020). New insights into arrestin recruitment to GPCRs. International Journal of Molecular Sciences, 21(14), 4949 (14 pp.). https://doi.org/10.3390/ijms21144949
Arrestin-1 engineering facilitates complex stabilization with native rhodopsin
Haider, R. S., Wilhelm, F., Rizk, A., Mutt, E., Deupi, X., Peterhans, C., … Ostermaier, M. K. (2019). Arrestin-1 engineering facilitates complex stabilization with native rhodopsin. Scientific Reports, 9(1), 439 (13 pp.). https://doi.org/10.1038/s41598-018-36881-4
Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins
Xie, Y., Mansouri, M., Rizk, A., & Berger, P. (2019). Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins. Scientific Reports, 9(1), 13342 (12 pp.). https://doi.org/10.1038/s41598-019-49646-4
Baculovirus for gene delivery to mammalian cells: past, present and future
Mansouri, M., & Berger, P. (2018). Baculovirus for gene delivery to mammalian cells: past, present and future. Plasmid, 98, 1-7. https://doi.org/10.1016/j.plasmid.2018.05.002
Multigene delivery in mammalian cells: recent advances and applications
Mansouri, M., & Berger, P. (2018). Multigene delivery in mammalian cells: recent advances and applications. Biotechnology Advances, 36(4), 871-879. https://doi.org/10.1016/j.biotechadv.2018.01.012
Baculovirus-based genome editing in primary cells
Mansouri, M., Ehsaei, Z., Taylor, V., & Berger, P. (2017). Baculovirus-based genome editing in primary cells. Plasmid, 90, 5-9. https://doi.org/10.1016/j.plasmid.2017.01.003
Highly efficient baculovirus-mediated multigene delivery in primary cells
Mansouri, M., Bellon-Echeverria, I., Rizk, A., Ehsaei, Z., Cianciolo Cosentino, C., Silva, C. S., … Berger, P. (2016). Highly efficient baculovirus-mediated multigene delivery in primary cells. Nature Communications, 7, 11529 (13 pp.). https://doi.org/10.1038/ncomms11529
Subcellular object quantification with Squassh3C and SquasshAnalyst
Rizk, A., Mansouri, M., Ballmer-Hofer, K., & Berger, P. (2015). Subcellular object quantification with Squassh3C and SquasshAnalyst. BioTechniques, 59(5), 309-311. https://doi.org/10.2144/000114352
NRP1 Presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation
Koch, S., Van Meeteren, L. A., Morin, E., Testini, C., Weström, S., Björkelund, H., … Claesson-Welsh, L. (2014). NRP1 Presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation. Developmental Cell, 28(6), 633-646. https://doi.org/10.1016/j.devcel.2014.02.010
Strategies for multigene expression in eukaryotic cells
Mansouri, M., & Berger, P. (2014). Strategies for multigene expression in eukaryotic cells. Plasmid, 75, 12-17. https://doi.org/10.1016/j.plasmid.2014.07.001
Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh
Rizk, A., Paul, G., Incardona, P., Bugarski, M., Mansouri, M., Niemann, A., … Sbalzarini, I. F. (2014). Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh. Nature Protocols, 9(3), 586-596. https://doi.org/10.1038/nprot.2014.037
Coordination of VEGF receptor trafficking and signaling by coreceptors
Nakayama, M., & Berger, P. (2013). Coordination of VEGF receptor trafficking and signaling by coreceptors. Experimental Cell Research, 319(9), 1340-1347. https://doi.org/10.1016/j.yexcr.2013.03.008
Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output
Ballmer-Hofer, K., Andersson, A. E., Ratcliffe, L. E., & Berger, P. (2011). Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output. Blood, 118(3), 816-826. https://doi.org/10.1182/blood-2011-01-328773
Integration of multiple expression cassettes into mammalian genomes in a single step
Berger, P., Kriz, A., Schmid, K., & Ballmer, K. (2011). Integration of multiple expression cassettes into mammalian genomes in a single step. (Protocol exchange). Springer Nature. https://doi.org/10.1038/protex.2011.249