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A DARPin promotes faster onset of botulinum neurotoxin A1 action
Leka, O., Wu, Y., Zanetti, G., Furler, S., Reinberg, T., Marinho, J., … Kammerer, R. A. (2023). A DARPin promotes faster onset of botulinum neurotoxin A1 action. Nature Communications, 14(1), 8317 (12 pp.). https://doi.org/10.1038/s41467-023-44102-4
Crystal structure of the catalytic domain of botulinum neurotoxin subtype A3
Leka, O., Wu, Y., Li, X., & Kammerer, R. A. (2021). Crystal structure of the catalytic domain of botulinum neurotoxin subtype A3. Journal of Biological Chemistry, 296, 100684 (8 pp.). https://doi.org/10.1016/j.jbc.2021.100684
Structural insights into the interaction of botulinum neurotoxin a with its neuronal receptor SV2C
Li, X., Brunner, C., Wu, Y., Leka, O., Schneider, G., & Kammerer, R. A. (2020). Structural insights into the interaction of botulinum neurotoxin a with its neuronal receptor SV2C. Toxicon, 175, 36-43. https://doi.org/10.1016/j.toxicon.2019.11.010
Crystal structure of a heterotetrameric katanin p60:p80 complex
Faltova, L., Jiang, K., Frey, D., Wu, Y., Capitani, G., Prota, A. E., … Kammerer, R. A. (2019). Crystal structure of a heterotetrameric katanin p60:p80 complex. Structure, 27(9), 1375-1383.e3. https://doi.org/10.1016/j.str.2019.07.002
Structural basis for the selective inhibition of c-Jun N-terminal kinase 1 determined by rigid DARPin-DARPin fusions
Wu, Y., Honegger, A., Batyuk, A., Mittl, P. R. E., & Plückthun, A. (2018). Structural basis for the selective inhibition of c-Jun N-terminal kinase 1 determined by rigid DARPin-DARPin fusions. Journal of Molecular Biology, 430(14), 2128-2138. https://doi.org/10.1016/j.jmb.2017.10.032
Rigidity of the extracellular part of HER2: evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions
Jost, C., Stüber, J. C., Honegger, A., Wu, Y., Batyuk, A., & Plückthun, A. (2017). Rigidity of the extracellular part of HER2: evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions. Protein Science, 26(9), 1796-1806. https://doi.org/10.1002/pro.3216
Rigidly connected multispecific artificial binders with adjustable geometries
Wu, Y., Batyuk, A., Honegger, A., Brandl, F., Mittl, P. R. E., & Plückthun, A. (2017). Rigidly connected multispecific artificial binders with adjustable geometries. Scientific Reports, 7(1), 11217 (11 pp.). https://doi.org/10.1038/s41598-017-11472-x