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Terbium-149 production: a focus on yield and quality improvement towards preclinical application
Favaretto, C., Grundler, P. V., Talip, Z., Köster, U., Johnston, K., Busslinger, S. D., … van der Meulen, N. P. (2024). Terbium-149 production: a focus on yield and quality improvement towards preclinical application. Scientific Reports, 14(1), 3284 (12 pp.). https://doi.org/10.1038/s41598-024-53610-2
First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([<sup>161</sup>Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum
Fricke, J., Westerbergh, F., McDougall, L., Favaretto, C., Christ, E., Nicolas, G. P., … Wild, D. (2024). First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum. European Journal of Nuclear Medicine and Molecular Imaging, 51, 2517-2519. https://doi.org/10.1007/s00259-024-06641-w
Development of wide range photon detection system for muonic X-ray spectroscopy
Mizuno, R., Niikura, M., Saito, T. Y., Matsuzaki, T., Sakurai, H., Amato, A., … Wang, C. (2024). Development of wide range photon detection system for muonic X-ray spectroscopy. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1060, 169029 (14 pp.). https://doi.org/10.1016/j.nima.2023.169029
In-vivo inhibition of neutral endopeptidase 1 results in higher absorbed tumor doses of [<sup>177</sup>Lu]Lu-PP-F11N in humans: the lumed phase 0b study
Rottenburger, C., Hentschel, M., Fürstner, M., McDougall, L., Kottoros, D., Kaul, F., … Wild, D. (2024). In-vivo inhibition of neutral endopeptidase 1 results in higher absorbed tumor doses of [177Lu]Lu-PP-F11N in humans: the lumed phase 0b study. EJNMMI Research, 14(1), 37 (13 pp.). https://doi.org/10.1186/s13550-024-01101-w
Relaxed fibronectin: a potential novel target for imaging endometriotic lesions
Trachsel, B., Imobersteg, S., Valpreda, G., Singer, G., Grabherr, R., Ormos, M., … Béhé, M. (2024). Relaxed fibronectin: a potential novel target for imaging endometriotic lesions. EJNMMI Research, 14(1), 17 (11 pp.). https://doi.org/10.1186/s13550-024-01070-0
Design and preclinical evaluation of a novel prostate-specific membrane antigen radioligand modified with a transthyretin binder
Vaccarin, C., Mapanao, A. K., Deberle, L. M., Becker, A. E., Borgna, F., Marzaro, G., … Müller, C. (2024). Design and preclinical evaluation of a novel prostate-specific membrane antigen radioligand modified with a transthyretin binder. Cancers, 16(7), 1262 (13 pp.). https://doi.org/10.3390/cancers16071262
Liquid chromatography ICP-MS to assess the stability of <sup>175</sup>Lu- and <sup>nat</sup>Ga-based tumor-targeting agents towards the development of <sup>177</sup>Lu- and <sup>68</sup>Ga-labeled radiopharmaceuticals
Wallimann, R. H., Hensinger, H., Müller, C., Schibli, R., Kneuer, R., & Schindler, P. (2024). Liquid chromatography ICP-MS to assess the stability of 175Lu- and natGa-based tumor-targeting agents towards the development of 177Lu- and 68Ga-labeled radiopharmaceuticals. Pharmaceutics, 16(3), 299 (13 pp.). https://doi.org/10.3390/pharmaceutics16030299
A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides
Beyer, D., Vaccarin, C., Deupi, X., Mapanao, A. K., Cohrs, S., Sozzi-Guo, F., … Müller, C. (2023). A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides. EJNMMI Research, 13(1), 32 (14 pp.). https://doi.org/10.1186/s13550-023-00979-2
The non-destructive investigation of a late antique knob bow fibula (Bügelknopffibel) from Kaiseraugst/CH using Muon Induced X-ray Emission (MIXE)
Biswas, S., Megatli-Niebel, I., Raselli, L., Simke, R., Cocolios, T. E., Deokar, N., … Amato, A. (2023). The non-destructive investigation of a late antique knob bow fibula (Bügelknopffibel) from Kaiseraugst/CH using Muon Induced X-ray Emission (MIXE). Heritage Science, 11, 43 (17 pp.). https://doi.org/10.1186/s40494-023-00880-0
Investigations using albumin binders to modify the tissue distribution profile of radiopharmaceuticals exemplified with folate radioconjugates
Busslinger, S. D., Becker, A. E., Vaccarin, C., Deberle, L. M., Renz, M. L., Groehn, V., … Müller, C. (2023). Investigations using albumin binders to modify the tissue distribution profile of radiopharmaceuticals exemplified with folate radioconjugates. Cancers, 15(17), 4259 (19 pp.). https://doi.org/10.3390/cancers15174259
<sup>161</sup>Tb-DOTATOC production using a fully automated disposable cassette system: a first step toward the introduction of <sup>161</sup>Tb into the clinic
Favaretto, C., Grundler, P. V., Talip, Z., Landolt, S., Sepini, L., Köster, U., … van der Meulen, N. P. (2023). 161Tb-DOTATOC production using a fully automated disposable cassette system: a first step toward the introduction of 161Tb into the clinic. Journal of Nuclear Medicine, 64(7), 1138-1144. https://doi.org/10.2967/jnumed.122.265268
GermanIum array for non-destructive testing (GIANT) setup for muon-induced x-ray emission (MIXE) at the Paul Scherrer Institute
Gerchow, L., Biswas, S., Janka, G., Vigo, C., Knecht, A., Vogiatzi, S. M., … Amato, A. (2023). GermanIum array for non-destructive testing (GIANT) setup for muon-induced x-ray emission (MIXE) at the Paul Scherrer Institute. Review of Scientific Instruments, 94(4), 045106 (15 pp.). https://doi.org/10.1063/5.0136178
Targeting mTORC1 activity to improve efficacy of radioligand therapy in cancer
Grzmil, M., Wiesmann, F., Schibli, R., & Behe, M. (2023). Targeting mTORC1 activity to improve efficacy of radioligand therapy in cancer. Cancers, 15(1), 17 (12 pp.). https://doi.org/10.3390/cancers15010017
An arrowhead made of meteoritic iron from the late Bronze Age settlement of Mörigen, Switzerland and its possible source
Hofmann, B. A., Bolliger Schreyer, S., Biswas, S., Gerchow, L., Wiebe, D., Schumann, M., … Amato, A. (2023). An arrowhead made of meteoritic iron from the late Bronze Age settlement of Mörigen, Switzerland and its possible source. Journal of Archaeological Science, 157, 105827 (10 pp.). https://doi.org/10.1016/j.jas.2023.105827
Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers
Pekeč, T., Venkatachalapathy, S., Shim, A. R., Paysan, D., Grzmil, M., Schibli, R., … Shivashankar, G. V. (2023). Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers. Scientific Reports, 13(1), 20662 (14 pp.). https://doi.org/10.1038/s41598-023-47287-2
Signaling network response to <em>α</em>-particle–targeted therapy with the <sup>225</sup>Ac-labeled minigastrin analog <sup>225</sup>Ac-PP-F11N reveals the radiosensitizing potential of histone deacetylase inhibitors
Qin, Y., Imobersteg, S., Frank, S., Blanc, A., Chiorazzo, T., Berger, P., … Grzmil, M. (2023). Signaling network response to α-particle–targeted therapy with the 225Ac-labeled minigastrin analog 225Ac-PP-F11N reveals the radiosensitizing potential of histone deacetylase inhibitors. Journal of Nuclear Medicine, 64(6), 873-879. https://doi.org/10.2967/jnumed.122.264597
Reducing kidney uptake of radiolabelled exendin-4 using variants of the renally cleavable linker MVK
Trachsel, B., Valpreda, G., Lutz, A., Schibli, R., Mu, L., & Béhé, M. (2023). Reducing kidney uptake of radiolabelled exendin-4 using variants of the renally cleavable linker MVK. EJNMMI Radiopharmacy and Chemistry, 8(1), 21 (11 pp.). https://doi.org/10.1186/s41181-023-00206-2
Albumin-binding and conventional PSMA ligands in combination with <sup>161</sup>Tb: biodistribution, dosimetry, and preclinical therapy
Tschan, V. J., Busslinger, S. D., Bernhardt, P., Grundler, P. V., Zeevaart, J. R., Köster, U., … Müller, C. (2023). Albumin-binding and conventional PSMA ligands in combination with 161Tb: biodistribution, dosimetry, and preclinical therapy. Journal of Nuclear Medicine, 64(10), 1625-1631. https://doi.org/10.2967/jnumed.123.265524
Inductively coupled plasma mass spectrometry - a valid method for the characterization of metal conjugates in view of the development of radiopharmaceuticals
Wallimann, R. H., Schindler, P., Hensinger, H., Tschan, V. J., Busslinger, S. D., Kneuer, R., … Schibli, R. (2023). Inductively coupled plasma mass spectrometry - a valid method for the characterization of metal conjugates in view of the development of radiopharmaceuticals. Molecular Pharmaceutics, 20(4), 2150-2158. https://doi.org/10.1021/acs.molpharmaceut.2c01092
Design and evaluation of novel albumin-binding folate radioconjugates: systematic approach of varying the linker entities
Benešová, M., Guzik, P., Deberle, L. M., Busslinger, S. D., Landolt, T., Schibli, R., & Müller, C. (2022). Design and evaluation of novel albumin-binding folate radioconjugates: systematic approach of varying the linker entities. Molecular Pharmaceutics, 19, 963-973. https://doi.org/10.1021/acs.molpharmaceut.1c00932
 

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