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The design of the n2EDM experiment
Ayres, N. J., Ban, G., Bienstman, L., Bison, G., Bodek, K., Bondar, V., … Zsigmond, G. (2021). The design of the n2EDM experiment. European Physical Journal C: Particles and Fields, 81(6), 512 (32 pp.). https://doi.org/10.1140/epjc/s10052-021-09298-z
Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals
Blum, T. B., Housset, D., Clabbers, M. T. B., van Genderen, E., Bacia-Verloop, M., Zander, U., … Abrahams, J. P. (2021). Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals. Acta Crystallographica Section D: Structural Biology, 77, 75-85. https://doi.org/10.1107/S2059798320014540
A robust, GFP-orthogonal photoswitchable inhibitor scaffold extends optical control over the microtubule cytoskeleton
Gao, L., Meiring, J. C. M., Kraus, Y., Wranik, M., Weinert, T., Pritzl, S. D., … Thorn-Seshold, O. (2021). A robust, GFP-orthogonal photoswitchable inhibitor scaffold extends optical control over the microtubule cytoskeleton. Cell Chemical Biology, 28(2), 228-241. https://doi.org/10.1016/j.chembiol.2020.11.007
Surface tensiometry of phase separated protein and polymer droplets by the sessile drop method
Ijavi, M., Style, R. W., Emmanouilidis, L., Kumar, A., Meier, S. M., Torzynski, A. L., … Dufresne, E. R. (2021). Surface tensiometry of phase separated protein and polymer droplets by the sessile drop method. Soft Matter, 17(6), 1655-1662. https://doi.org/10.1039/d0sm01319f
Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site
Matthew, S., Chen, Q. Y., Ratnayake, R., Fermaintt, C. S., Lucena-Agell, D., Bonato, F., … Luesch, H. (2021). Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site. Proceedings of the National Academy of Sciences of the United States of America PNAS, 118(9), e2021847118 (11 pp.). https://doi.org/10.1073/pnas.2021847118
Comprehensive analysis of binding sites in tubulin
Mühlethaler, T., Gioia, D., Prota, A. E., Sharpe, M. E., Cavalli, A., & Steinmetz, M. O. (2021). Comprehensive analysis of binding sites in tubulin. Angewandte Chemie International Edition, 60(24), 13331-13342. https://doi.org/10.1002/anie.202100273
Centriole length control
Sharma, A., Olieric, N., & Steinmetz, M. O. (2021). Centriole length control. Current Opinion in Structural Biology, 66, 89-95. https://doi.org/10.1016/j.sbi.2020.10.011
Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in <em>Streptomyces</em>
Xiao, X., Willemse, J., Voskamp, P., Li, X., Prota, A. E., Lamers, M., … van Wezel, G. P. (2021). Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in Streptomyces. Open Biology, 11(2), 200409 (14 pp.). https://doi.org/10.1098/rsob.200409
The mechanism of kinesin inhibition by kinesin binding protein
Atherton, J., Hummel, J. J. A., Olieric, N., Locke, J., Peña, A., Rosenfeld, S. S., … Moores, C. A. (2020). The mechanism of kinesin inhibition by kinesin binding protein. eLife, 9, e61481 (30 pp.). https://doi.org/10.7554/eLife.61481
Structural model for differential cap maturation at growing microtubule ends
Estévez-Gallego, J., Josa-Prado, F., Ku, S., Buey, R. M., Balaguer, F. A., Prota, A. E., … Oliva, M. A. (2020). Structural model for differential cap maturation at growing microtubule ends. eLife, 9, e50155 (26 pp.). https://doi.org/10.7554/eLife.50155
Structural refinement of the tubulin ligand (+)-discodermolide to attenuate chemotherapy-mediated senescence
Guo, B., Rodriguez-Gabin, A., Prota, A. E., Mühlethaler, T., Zhang, N., Ye, K., … McDaid, H. M. (2020). Structural refinement of the tubulin ligand (+)-discodermolide to attenuate chemotherapy-mediated senescence. Molecular Pharmacology, 98(2), 156-167. https://doi.org/10.1124/mol.119.117457
Pharmaceutical-grade rigosertib is a microtubule-destabilizing agent
Jost, M., Chen, Y., Gilbert, L. A., Horlbeck, M. A., Krenning, L., Menchon, G., … Weissman, J. S. (2020). Pharmaceutical-grade rigosertib is a microtubule-destabilizing agent. Molecular Cell, 79(1), 191-198.e3. https://doi.org/10.1016/j.molcel.2020.06.008
Sensing form - finger gaiting as key to tactile object exploration - a data glove analysis of a prototypical daily task
Krammer, W., Missimer, J. H., Habegger, S., Pastore-Wapp, M., Wiest, R., & Weder, B. J. (2020). Sensing form - finger gaiting as key to tactile object exploration - a data glove analysis of a prototypical daily task. Journal of NeuroEngineering and Rehabilitation, 17(133), 1-17. https://doi.org/10.1186/s12984-020-00755-6
Advances in long-wavelength native phasing at X-ray free-electron lasers
Nass, K., Cheng, R., Vera, L., Mozzanica, A., Redford, S., Ozerov, D., … Milne, C. J. (2020). Advances in long-wavelength native phasing at X-ray free-electron lasers. IUCrJ, 7, 965-975. https://doi.org/10.1107/S2052252520011379
Structural basis of noscapine activation for tubulin binding
Oliva, M. A., Prota, A. E., Rodríguez-Salarichs, J., Bennani, Y. L., Jiménez-Barbero, J., Bargsten, K., … Díaz, J. F. (2020). Structural basis of noscapine activation for tubulin binding. Journal of Medicinal Chemistry, 63(15), 8495-8501. https://doi.org/10.1021/acs.jmedchem.0c00855
Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules
Rodríguez-García, R., Volkov, V. A., Chen, C. Y., Katrukha, E. A., Olieric, N., Aher, A., … Akhmanova, A. (2020). Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules. Current Biology, 30(6), 972-987. https://doi.org/10.1016/j.cub.2020.01.036
WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity
Steib, E., Laporte, M. H., Gambarotto, D., Olieric, N., Zheng, C., Borgers, S., … Hamel, V. (2020). WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity. eLife, 9, e57205 (28 pp.). https://doi.org/10.7554/ELIFE.57205
Functional and structural insights into a novel promiscuous ketoreductase of the lugdunomycin biosynthetic pathway
Xiao, X., Elsayed, S. S., Wu, C., van der Heul, H. U., Metsä-Ketelä, M., Du, C., … van Wezel, G. P. (2020). Functional and structural insights into a novel promiscuous ketoreductase of the lugdunomycin biosynthetic pathway. ACS Chemical Biology, 15(9), 2529-2538. https://doi.org/10.1021/acschembio.0c00564
Early prediction of long-term tactile object recognition performance after sensorimotor stroke
Abela, E., Missimer, J. H., Pastore-Wapp, M., Krammer, W., Wiest, R., & Weder, B. J. (2019). Early prediction of long-term tactile object recognition performance after sensorimotor stroke. Cortex, 115, 264-279. https://doi.org/10.1016/j.cortex.2019.01.018
Structural determinants of microtubule minus end preference in CAMSAP CKK domains
Atherton, J., Luo, Y., Xiang, S., Yang, C., Rai, A., Jiang, K., … Moores, C. A. (2019). Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nature Communications, 10(1), 5236 (16 pp.). https://doi.org/10.1038/s41467-019-13247-6
 

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