| Michaelis-Menten quantification of ligand signaling bias applied to the promiscuous vasopressin V2 receptor
Heydenreich, F. M., Plouffe, B., Rizk, A., Milić, D., Zhou, J., Breton, B., … Veprintsev, D. B. (2022). Michaelis-Menten quantification of ligand signaling bias applied to the promiscuous vasopressin V2 receptor. Molecular Pharmacology, 102(3), 139-149. https://doi.org/10.1124/molpharm.122.000497 |
| Arrestin-1 engineering facilitates complex stabilization with native rhodopsin
Haider, R. S., Wilhelm, F., Rizk, A., Mutt, E., Deupi, X., Peterhans, C., … Ostermaier, M. K. (2019). Arrestin-1 engineering facilitates complex stabilization with native rhodopsin. Scientific Reports, 9(1), 439 (13 pp.). https://doi.org/10.1038/s41598-018-36881-4 |
| Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins
Xie, Y., Mansouri, M., Rizk, A., & Berger, P. (2019). Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins. Scientific Reports, 9(1), 13342 (12 pp.). https://doi.org/10.1038/s41598-019-49646-4 |
| ScFvs as allosteric inhibitors of VEGFR-2: novel tools to harness VEGF signaling
Ballmer-Hofer, K., Hyde, C. A. C., Schleier, T., & Avramovic, D. (2018). ScFvs as allosteric inhibitors of VEGFR-2: novel tools to harness VEGF signaling. International Journal of Molecular Sciences, 19(5), 1334 (15 pp.). https://doi.org/10.3390/ijms19051334 |
| Baculovirus for gene delivery to mammalian cells: past, present and future
Mansouri, M., & Berger, P. (2018). Baculovirus for gene delivery to mammalian cells: past, present and future. Plasmid, 98, 1-7. https://doi.org/10.1016/j.plasmid.2018.05.002 |
| Multigene delivery in mammalian cells: recent advances and applications
Mansouri, M., & Berger, P. (2018). Multigene delivery in mammalian cells: recent advances and applications. Biotechnology Advances, 36(4), 871-879. https://doi.org/10.1016/j.biotechadv.2018.01.012 |
| Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling
Thieltges, K. M., Avramovic, D., Piscitelli, C. L., Markovic-Mueller, S., Binz, H. K., & Ballmer-Hofer, K. (2018). Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling. Angiogenesis, 21(3), 533-543. https://doi.org/10.1007/s10456-018-9606-9 |
| Exome sequencing of plasma DNA portrays the mutation landscape of colorectal cancer and discovers mutated VEGFR2 receptors as modulators of antiangiogenic therapies
Toledo, R. A., Garralda, E., Mitsi, M., Pons, T., Monsech, J., Vega, E., … Hidalgo, M. (2018). Exome sequencing of plasma DNA portrays the mutation landscape of colorectal cancer and discovers mutated VEGFR2 receptors as modulators of antiangiogenic therapies. Clinical Cancer Research, 24(15), 3550-3559. https://doi.org/10.1158/1078-0432.CCR-18-0103 |
| Comprehensive analysis of the role of arrestin residues in receptor binding
Haider, R. S., Rizk, A., Schertler, G. F. X., & Ostermaier, M. K. (2017). Comprehensive analysis of the role of arrestin residues in receptor binding. In V. V. Gurevich (Ed.), The structural basis of arrestin functions (pp. 83-102). https://doi.org/10.1007/978-3-319-57553-7_7 |
| High-throughput mutagenesis using a two-fragment PCR approach
Heydenreich, F. M., Miljuš, T., Jaussi, R., Benoit, R., Milić, D., & Veprintsev, D. B. (2017). High-throughput mutagenesis using a two-fragment PCR approach. Scientific Reports, 7, 6787 (11 pp.). https://doi.org/10.1038/s41598-017-07010-4 |
| Baculovirus-based genome editing in primary cells
Mansouri, M., Ehsaei, Z., Taylor, V., & Berger, P. (2017). Baculovirus-based genome editing in primary cells. Plasmid, 90, 5-9. https://doi.org/10.1016/j.plasmid.2017.01.003 |
| Structure of the full-length VEGFR-1 extracellular domain in complex with VEGF-A
Markovic-Mueller, S., Stuttfeld, E., Asthana, M., Weinert, T., Bliven, S., Goldie, K. N., … Ballmer-Hofer, K. (2017). Structure of the full-length VEGFR-1 extracellular domain in complex with VEGF-A. Structure, 25(2), 341-352. https://doi.org/10.1016/j.str.2016.12.012 |
| Full-length fibronectin drives fibroblast accumulation at the surface of collagen microtissues during cell-induced tissue morphogenesis
Foolen, J., Shiu, J. Y., Mitsi, M., Zhang, Y., Chen, C. S., & Vogel, V. (2016). Full-length fibronectin drives fibroblast accumulation at the surface of collagen microtissues during cell-induced tissue morphogenesis. PLoS One, 11(8), e0160369 (24 pp.). https://doi.org/10.1371/journal.pone.0160369 |
| SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture
Hilbert, M., Noga, A., Frey, D., Hamel, V., Guichard, P., Kraatz, S. H. W., … Steinmetz, M. O. (2016). SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature Cell Biology, 18(4), 393-403. https://doi.org/10.1038/ncb3329 |
| Synthesis of a new T-shaped heterobinuclear Pt<sup>0</sup>-Au<sup>I</sup> complex [(<em>t</em>-Bu<sub>3</sub>P)<sub>2</sub>PtAu(PPh<sub>3</sub>)]BF<sub>4</sub> from trinuclear gold cluster complex [(PPh<sub>3</sub>)Au]<sub>3</sub>(<em>μ</em>-O)BF<sub>4</s
Jamalia, S., Ashtiania, M. M., & Milić, D. (2016). Synthesis of a new T-shaped heterobinuclear Pt0-AuI complex [(t-Bu3P)2PtAu(PPh3)]BF4 from trinuclear gold cluster complex [(PPh3)Au]3(μ-O)BF4. Scientia Iranica, 23(3), 1089-1094. https://doi.org/10.24200/sci.2016.3878 |
| The human centriolar protein CEP135 contains a two-stranded coiled-coil domain critical for microtubule binding
Kraatz, S., Guichard, P., Obbineni, J. M., Olieric, N., Hatzopoulos, G. N., Hilbert, M., … Steinmetz, M. O. (2016). The human centriolar protein CEP135 contains a two-stranded coiled-coil domain critical for microtubule binding. Structure, 24(8), 1358-1371. https://doi.org/10.1016/j.str.2016.06.011 |
| Highly efficient baculovirus-mediated multigene delivery in primary cells
Mansouri, M., Bellon-Echeverria, I., Rizk, A., Ehsaei, Z., Cianciolo Cosentino, C., Silva, C. S., … Berger, P. (2016). Highly efficient baculovirus-mediated multigene delivery in primary cells. Nature Communications, 7, 11529 (13 pp.). https://doi.org/10.1038/ncomms11529 |
| Structure of the BoNT/A1 - Receptor complex
Benoit, R. M., Frey, D., Wieser, M. M., Thieltges, K. M., Jaussi, R., Capitani, G., & Kammerer, R. A. (2015). Structure of the BoNT/A1 - Receptor complex. Toxicon, 107(Part A), 25-31. https://doi.org/10.1016/j.toxicon.2015.08.002 |
| Universal allosteric mechanism for Gα activation by GPCRs
Flock, T., Ravarani, C. N. J., Sun, D., Venkatakrishnan, A. J., Kayikci, M., Tate, C. G., … Babu, M. M. (2015). Universal allosteric mechanism for Gα activation by GPCRs. Nature, 524, 173-179. https://doi.org/10.1038/nature14663 |
| Large scale expression and purification of the rat 5-HT<sub>2c</sub> receptor
He, X., Robertson, N., Jazayeri, A., Geroni Gasperina, A., Schertler, G., & Li, X. (2015). Large scale expression and purification of the rat 5-HT2c receptor. Protein Expression and Purification, 106, 1-9. https://doi.org/10.1016/j.pep.2014.10.010 |
