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Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
Cellini, A., Shankar, M. K., Nimmrich, A., Hunt, L. A., Monrroy, L., Mutisya, J., … Westenhoff, S. (2024). Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography. Nature Chemistry. https://doi.org/10.1038/s41557-023-01413-9
Transcriptional changes are tightly coupled to chromatin reorganization during cellular aging
Braunger, J. M., Cammarata, L. V., Sornapudi, T. R., Uhler, C., & Shivashankar, G. V. (2023). Transcriptional changes are tightly coupled to chromatin reorganization during cellular aging. Aging cell. https://doi.org/10.1111/acel.14056
Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs
Carrillo, M., Mason, T. J., Karpik, A., Martiel, I., Kepa, M. W., McAuley, K. E., … Padeste, C. (2023). Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs. IUCrJ, 10(6), 678-693. https://doi.org/10.1107/S2052252523007595
Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies
Challa, K., Paysan, D., Leiser, D., Sauder, N., Weber, D. C., & Shivashankar, G. V. (2023). Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies. npj Precision Oncology, 7, 135 (13 pp.). https://doi.org/10.1038/s41698-023-00484-8
Kinetic reconstruction of free energies as a function of multiple order parameters
Goswami, Y., & Sastry, S. (2023). Kinetic reconstruction of free energies as a function of multiple order parameters. Journal of Chemical Physics, 158(14), 144502 (17 pp.). https://doi.org/10.1063/5.0144338
Cross interactions between Apolipoprotein E and amyloid proteins in neurodegenerative diseases
Loch, R. A., Wang, H., Perálvarez-Marín, A., Berger, P., Nielsen, H., Chroni, A., & Luo, J. (2023). Cross interactions between Apolipoprotein E and amyloid proteins in neurodegenerative diseases. Computational and Structural Biotechnology Journal, 21, 1189-1204. https://doi.org/10.1016/j.csbj.2023.01.022
Polymer brush structures functionalized with molecular beacon for point-of-care diagnostics
Moazeni, M., Berger, P., & Padeste, C. (2023). Polymer brush structures functionalized with molecular beacon for point-of-care diagnostics. Micro and Nano Engineering, 19, 100184 (9 pp.). https://doi.org/10.1016/j.mne.2023.100184
Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers
Pekeč, T., Venkatachalapathy, S., Shim, A. R., Paysan, D., Grzmil, M., Schibli, R., … Shivashankar, G. V. (2023). Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers. Scientific Reports, 13(1), 20662 (14 pp.). https://doi.org/10.1038/s41598-023-47287-2
Signaling network response to <em>α</em>-particle–targeted therapy with the <sup>225</sup>Ac-labeled minigastrin analog <sup>225</sup>Ac-PP-F11N reveals the radiosensitizing potential of histone deacetylase inhibitors
Qin, Y., Imobersteg, S., Frank, S., Blanc, A., Chiorazzo, T., Berger, P., … Grzmil, M. (2023). Signaling network response to α-particle–targeted therapy with the 225Ac-labeled minigastrin analog 225Ac-PP-F11N reveals the radiosensitizing potential of histone deacetylase inhibitors. Journal of Nuclear Medicine, 64(6), 873-879. https://doi.org/10.2967/jnumed.122.264597
Implanting mechanically reprogrammed fibroblasts for aged tissue regeneration and wound healing
Roy, B., Pekec, T., Yuan, L., & Shivashankar, G. V. (2023). Implanting mechanically reprogrammed fibroblasts for aged tissue regeneration and wound healing. Aging cell (14 pp.). https://doi.org/10.1111/acel.14032
A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers
Wranik, M., Kepa, M. W., Beale, E. V., James, D., Bertrand, Q., Weinert, T., … Standfuss, J. (2023). A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers. Nature Communications, 14(1), 7956 (12 pp.). https://doi.org/10.1038/s41467-023-43523-5
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography
Wranik, M., Weinert, T., Slavov, C., Masini, T., Furrer, A., Gaillard, N., … Standfuss, J. (2023). Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography. Nature Communications, 14(1), 903 (12 pp.). https://doi.org/10.1038/s41467-023-36481-5
Ice nucleation imaged with X-ray spectro-microscopy
Alpert, P. A., Boucly, A., Yang, S., Yang, H., Kilchhofer, K., Luo, Z., … Watts, B. (2022). Ice nucleation imaged with X-ray spectro-microscopy. Environmental Science: Atmospheres, 2(3), 335-351. https://doi.org/10.1039/D1EA00077B
Rotation characteristics of acoustically actuated thin-film rotors in air and water
Jia, S., Sato, Y., Lim, R. Y. H., & Tsujino, S. (2022). Rotation characteristics of acoustically actuated thin-film rotors in air and water. In IEEE international ultrasonics symposium. IUS 2022. Symposium proceedings (p. (2 pp.). https://doi.org/10.1109/IUS54386.2022.9958207
Size and shape dependent rotation characteristics of thin film ultrasonic rotors
Jia, S., Sato, Y., & Tsujino, S. (2022). Size and shape dependent rotation characteristics of thin film ultrasonic rotors. Applied Physics Letters, 121(25), 254102 (6 pp.). https://doi.org/10.1063/5.0126000
Acoustic levitation and rotation of thin films and their application for room temperature protein crystallography
Kepa, M. W., Tomizaki, T., Sato, Y., Ozerov, D., Sekiguchi, H., Yasuda, N., … Tsujino, S. (2022). Acoustic levitation and rotation of thin films and their application for room temperature protein crystallography. Scientific Reports, 12, 5349 (14 pp.). https://doi.org/10.1038/s41598-022-09167-z
Thermoplastic microfluidics
Kristiansen, P. M., Karpik, A., Werder, J., Guilherme, M., & Grob, M. (2022). Thermoplastic microfluidics. In M. Rasponi (Ed.), Methods in molecular biology: Vol. 2373. Organ-on-a-chip. Methods and protocols (pp. 39-55). https://doi.org/10.1007/978-1-0716-1693-2_3
Poly(methyl methacrylate)-based nanofluidic device for rapid and multiplexed serological antibody detection of SARS-CoV-2
Mortelmans, T., Kazazis, D., Padeste, C., Berger, P., Li, X., & Ekinci, Y. (2022). Poly(methyl methacrylate)-based nanofluidic device for rapid and multiplexed serological antibody detection of SARS-CoV-2. ACS Applied Nano Materials, 5(1), 517-526. https://doi.org/10.1021/acsanm.1c03309
Rational design of a novel tubulin inhibitor with a unique mechanism of action
Mühlethaler, T., Milanos, L., Ortega, J. A., Blum, T. B., Gioia, D., Roy, B., … Steinmetz, M. O. (2022). Rational design of a novel tubulin inhibitor with a unique mechanism of action. Angewandte Chemie International Edition, 61(25), e202204052 (11 pp.). https://doi.org/10.1002/anie.202204052
Variations on a theme: crystal forms of the amino-acid transporter MhsT
Neumann, C., Focht, D., Trampari, S., Lyons, J. A., & Nissen, P. (2022). Variations on a theme: crystal forms of the amino-acid transporter MhsT. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 78, 297-305. https://doi.org/10.1107/S2053230X22007154