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  • (-) Publication Year = 2020
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Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering
Aalbers, F. S., Fürst, M. J. L. J., Rovida, S., Trajkovic, M., Rubén Gómez Castellanos, J., Bartsch, S., … Fraaije, M. W. (2020). Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering. eLife, 9, e54639 (18 pp.). https://doi.org/10.7554/eLife.54639
Fabrication and characterization of ice templated membrane supports from Portland cement
Abdullayev, A., Kamm, P. H., Bekheet, M. F., & Gurlo, A. (2020). Fabrication and characterization of ice templated membrane supports from Portland cement. Membranes, 10(5), 93 (13 pp.). https://doi.org/10.3390/membranes10050093
Near-atomic resolution structures of interdigitated nucleosome fibres
Adhireksan, Z., Sharma, D., Lee, P. L., & Davey, C. A. (2020). Near-atomic resolution structures of interdigitated nucleosome fibres. Nature Communications, 11(1), 4747 (13 pp.). https://doi.org/10.1038/s41467-020-18533-2
A protein tertiary structure mimetic modulator of the Hippo signalling pathway
Adihou, H., Gopalakrishnan, R., Förster, T., Guéret, S. M., Gasper, R., Geschwindner, S., … Waldmann, H. (2020). A protein tertiary structure mimetic modulator of the Hippo signalling pathway. Nature Communications, 11(1), 5425 (10 pp.). https://doi.org/10.1038/s41467-020-19224-8
Magnetization spin reversal and neutron diffraction study of polycrystalline Tb<sub>0.55</sub>Sr<sub>0.45</sub>MnO<sub>3</sub>
Agarwal, H., Alonso, J. A., Muñoz, Á., Choudhary, R. J., Srivastava, O. N., & Shaz, M. A. (2020). Magnetization spin reversal and neutron diffraction study of polycrystalline Tb0.55Sr0.45MnO3. Journal of Alloys and Compounds, 845, 156355 (12 pp.). https://doi.org/10.1016/j.jallcom.2020.156355
From static alteration to mylonitization: a nano- to micrometric study of chloritization in granitoids with implications for equilibrium and percolation length scales
Airaghi, L., Dubacq, B., Verlaguet, A., Bourdelle, F., Bellahsen, N., & Gloter, A. (2020). From static alteration to mylonitization: a nano- to micrometric study of chloritization in granitoids with implications for equilibrium and percolation length scales. Contributions to Mineralogy and Petrology, 175(11), 108 (25 pp.). https://doi.org/10.1007/s00410-020-01749-2
Alternative catalytic residues in the active site of Esco acetyltransferases
Ajam, T., De, I., Petkau, N., Whelan, G., Pena, V., & Eichele, G. (2020). Alternative catalytic residues in the active site of Esco acetyltransferases. Scientific Reports, 10(1), 9828 (13 pp.). https://doi.org/10.1038/s41598-020-66795-z
Discovery of LOU064 (remibrutinib), a potent and highly selective covalent inhibitor of Bruton's tyrosine kinase
Angst, D., Gessier, F., Janser, P., Vulpetti, A., Wälchli, R., Beerli, C., … Cenni, B. (2020). Discovery of LOU064 (remibrutinib), a potent and highly selective covalent inhibitor of Bruton's tyrosine kinase. Journal of Medicinal Chemistry, 63(10), 5102-5118. https://doi.org/10.1021/acs.jmedchem.9b01916
The ABC exporter IrtAB imports and reduces mycobacterial siderophores
Arnold, F. M., Weber, M. S., Gonda, I., Gallenito, M. J., Adenau, S., Egloff, P., … Seeger, M. A. (2020). The ABC exporter IrtAB imports and reduces mycobacterial siderophores. Nature, 580(7803), 413-417. https://doi.org/10.1038/s41586-020-2136-9
Two RNA tunnel inhibitors bind in highly conserved sites in dengue virus NS5 polymerase: structural and functional studies
Arora, R., Liew, C. W., Soh, T. S., Otoo, D. A., Seh, C. C., Yue, K., … Lim, S. P. (2020). Two RNA tunnel inhibitors bind in highly conserved sites in dengue virus NS5 polymerase: structural and functional studies. Journal of Virology, 94(24), e01130-20 (17 pp.). https://doi.org/10.1128/JVI.01130-20
Structures in tetrahydrofolate methylation in desulfitobacterial glycine betaine metabolism at atomic resolution
Badmann, T., & Groll, M. (2020). Structures in tetrahydrofolate methylation in desulfitobacterial glycine betaine metabolism at atomic resolution. ChemBioChem, 21(6), 776-779. https://doi.org/10.1002/cbic.201900515
On-surface synthesis of nonmetal porphyrins
Baklanov, A., Garnica, M., Robert, A., Bocquet, M. L., Seufert, K., Küchle, J. T., … Auwärter, W. (2020). On-surface synthesis of nonmetal porphyrins. Journal of the American Chemical Society, 142(4), 1871-1881. https://doi.org/10.1021/jacs.9b10711
Expanding the application range of microbial oxidoreductases by an alcohol dehydrogenase from <em>Comamonas testosteroni</em> with a broad substrate spectrum and pH profile
Bakonyi, D., Toelzer, C., Stricker, M., Hummel, W., Niefind, K., & Gröger, H. (2020). Expanding the application range of microbial oxidoreductases by an alcohol dehydrogenase from Comamonas testosteroni with a broad substrate spectrum and pH profile. Catalysts, 10(11), 1281 (14 pp.). https://doi.org/10.3390/catal10111281
Targeting cavity-creating p53 cancer mutations with small-molecule stabilizers: the Y220X paradigm
Bauer, M. R., Krämer, A., Settanni, G., Jones, R. N., Ni, X., Khan Tareque, R., … Joerger, A. C. (2020). Targeting cavity-creating p53 cancer mutations with small-molecule stabilizers: the Y220X paradigm. ACS Chemical Biology, 15(3), 657-668. https://doi.org/10.1021/acschembio.9b00748
Small-molecule inhibitors of METTL3, the major human epitranscriptomic writer
Bedi, R. K., Huang, D., Eberle, S. A., Wiedmer, L., Śledź, P., & Caflisch, A. (2020). Small-molecule inhibitors of METTL3, the major human epitranscriptomic writer. ChemMedChem, 15(9), 744-748. https://doi.org/10.1002/cmdc.202000011
Synthesis, structure and NH<sub>3</sub> sorption properties of mixed Mg<sub>1-x</sub>Mn<sub>x</sub>(NH<sub>3</sub>)<sub>6</sub>Cl<sub>2</sub> ammines
Berdiyeva, P., Karabanova, A., Grinderslev, J. B., Johnsen, R. E., Blanchard, D., Hauback, B. C., & Deledda, S. (2020). Synthesis, structure and NH3 sorption properties of mixed Mg1-xMnx(NH3)6Cl2 ammines. Energies, 13(11), 2746 (14 pp.). https://doi.org/10.3390/en13112746
Identification of BRaf-sparing amino-thienopyrimidines with potent IRE1α inhibitory activity
Beveridge, R. E., Wallweber, H. A., Ashkenazi, A., Beresini, M., Clark, K. R., Gibbons, P., … Braun, M. G. (2020). Identification of BRaf-sparing amino-thienopyrimidines with potent IRE1α inhibitory activity. ACS Medicinal Chemistry Letters, 11(12), 2389-2396. https://doi.org/10.1021/acsmedchemlett.0c00344
Structural basis for the recognition of transiently structured AU-rich elements by Roquin
Binas, O., Tants, J. N., Peter, S. A., Janowski, R., Davydova, E., Braun, J., … Schlundt, A. (2020). Structural basis for the recognition of transiently structured AU-rich elements by Roquin. Nucleic Acids Research, 48(13), 7385-7403. https://doi.org/10.1093/nar/gkaa465
Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors
Bokhovchuk, F., Mesrouze, Y., Delaunay, C., Martin, T., Villard, F., Meyerhofer, M., … Chène, P. (2020). Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors. Protein Science, 29(2), 509-520. https://doi.org/10.1002/pro.3775
'Drc', a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses
Boon, M., De Zitter, E., De Smet, J., Wagemans, J., Voet, M., Pennemann, F. L., … Lavigne, R. (2020). 'Drc', a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses. Nucleic Acids Research, 48(1), 445-459. https://doi.org/10.1093/nar/gkz1048
 

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