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Engineering of a functional γ-tocopherol transfer protein
Aeschimann, W., Kammer, S., Staats, S., Schneider, P., Schneider, G., Rimbach, G., … Stocker, A. (2021). Engineering of a functional γ-tocopherol transfer protein. Redox Biology, 38, 101773 (11 pp.). https://doi.org/10.1016/j.redox.2020.101773
Conformational editing of intrinsically disordered protein by α-methylation
Bauer, V., Schmidtgall, B., Gógl, G., Dolenc, J., Osz, J., Nominé, Y., … Torbeev, V. (2021). Conformational editing of intrinsically disordered protein by α-methylation. Chemical Science. https://doi.org/10.1039/D0SC04482B
Catanthus, an extinct magnoliid flower from the early cretaceous of portugal
Friis, E. M., Crane, P. R., & Pedersen, K. R. (2021). Catanthus, an extinct magnoliid flower from the early cretaceous of portugal. International Journal of Plant Sciences, 182(1), 28-45. https://doi.org/10.1086/711081
Insulin binding to the analytical antibody sandwich pair OXI‐005 and HUI‐018: epitope mapping and binding properties
Johansson, E., Wu, X., Yu, B., Yang, Z., Cao, Z., Wiberg, C., … Poulsen, F. (2021). Insulin binding to the analytical antibody sandwich pair OXI‐005 and HUI‐018: epitope mapping and binding properties. Protein Science, 30(2), 485-496. https://doi.org/10.1002/pro.4009
Gas channel rerouting in a primordial enzyme: structural insights of the carbon-monoxide dehydrogenase/acetyl-CoA synthase complex from the acetogen <em>Clostridium autoethanogenum</em>
Lemaire, O. N., & Wagner, T. (2021). Gas channel rerouting in a primordial enzyme: structural insights of the carbon-monoxide dehydrogenase/acetyl-CoA synthase complex from the acetogen Clostridium autoethanogenum. Biochimica et Biophysica Acta: Bioenergetics, 1862(1), 148330 (14 pp.). https://doi.org/10.1016/j.bbabio.2020.148330
Reprogramming substrate and catalytic promiscuity of tryptophan prenyltransferases
Ostertag, E., Zheng, L., Broger, K., Stehle, T., Li, S. M., & Zocher, G. (2021). Reprogramming substrate and catalytic promiscuity of tryptophan prenyltransferases. Journal of Molecular Biology, 433(2), 166726 (14 pp.). https://doi.org/10.1016/j.jmb.2020.11.025
Triggering closure of a sialic acid TRAP transporter substrate binding protein through binding of natural or artificial substrates
Peter, M. F., Gebhardt, C., Glaenzer, J., Schneberger, N., de Boer, M., Thomas, G. H., … Hagelueken, G. (2021). Triggering closure of a sialic acid TRAP transporter substrate binding protein through binding of natural or artificial substrates. Journal of Molecular Biology, 433(3), 166756 (15 pp.). https://doi.org/10.1016/j.jmb.2020.166756
Measurement of ionization quenching in plastic scintillators
Pöschl, T., Greenwald, D., Losekamm, M. J., & Paul, S. (2021). Measurement of ionization quenching in plastic scintillators. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 988, 164865 (8 pp.). https://doi.org/10.1016/j.nima.2020.164865
Divalent cations influence the dimerization mode of murine S100A9 protein by modulating its disulfide bond pattern
Signor, L., Paris, T., Mas, C., Picard, A., Lutfalla, G., Boeri Erba, E., & Yatime, L. (2021). Divalent cations influence the dimerization mode of murine S100A9 protein by modulating its disulfide bond pattern. Journal of Structural Biology, 213(1), 107689 (16 pp.). https://doi.org/10.1016/j.jsb.2020.107689
Development of autotaxin inhibitors: a series of tetrazole cinnamides
Thomson, C. G., Le Grand, D., Dowling, M., Beattie, D., Elphick, L., Faller, M., … Zink, F. (2021). Development of autotaxin inhibitors: a series of tetrazole cinnamides. Bioorganic and Medicinal Chemistry Letters, 31, 127663 (7 pp.). https://doi.org/10.1016/j.bmcl.2020.127663
Does targeting Arg98 of FimH lead to high affinity antagonists?
Tomašič, T., Rabbani, S., Jakob, R. P., Reisner, A., Jakopin, Ž., Maier, T., … Anderluh, M. (2021). Does targeting Arg98 of FimH lead to high affinity antagonists? European Journal of Medicinal Chemistry, 211, 113093 (16 pp.). https://doi.org/10.1016/j.ejmech.2020.113093
Structure based design of bicyclic Peptide inhibitors of RbAp48
't Hart, P., Hommen, P., Noisier, A., Krzyzanowski, A., Schüler, D., Porfetye, A. T., … Waldmann, H. (2020). Structure based design of bicyclic Peptide inhibitors of RbAp48. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.202009749
Near-atomic resolution structures of interdigitated nucleosome fibres
Adhireksan, Z., Sharma, D., Lee, P. L., & Davey, C. A. (2020). Near-atomic resolution structures of interdigitated nucleosome fibres. Nature Communications, 11(1), 4747 (13 pp.). https://doi.org/10.1038/s41467-020-18533-2
Magnetization spin reversal and neutron diffraction study of polycrystalline Tb<sub>0.55</sub>Sr<sub>0.45</sub>MnO<sub>3</sub>
Agarwal, H., Alonso, J. A., Muñoz, Á., Choudhary, R. J., Srivastava, O. N., & Shaz, M. A. (2020). Magnetization spin reversal and neutron diffraction study of polycrystalline Tb0.55Sr0.45MnO3. Journal of Alloys and Compounds, 845, 156355 (12 pp.). https://doi.org/10.1016/j.jallcom.2020.156355
Alternative catalytic residues in the active site of Esco acetyltransferases
Ajam, T., De, I., Petkau, N., Whelan, G., Pena, V., & Eichele, G. (2020). Alternative catalytic residues in the active site of Esco acetyltransferases. Scientific Reports, 10(1), 9828 (13 pp.). https://doi.org/10.1038/s41598-020-66795-z
Discovery of LOU064 (remibrutinib), a potent and highly selective covalent inhibitor of Bruton's tyrosine kinase
Angst, D., Gessier, F., Janser, P., Vulpetti, A., Wälchli, R., Beerli, C., … Cenni, B. (2020). Discovery of LOU064 (remibrutinib), a potent and highly selective covalent inhibitor of Bruton's tyrosine kinase. Journal of Medicinal Chemistry, 63(10), 5102-5118. https://doi.org/10.1021/acs.jmedchem.9b01916
The ABC exporter IrtAB imports and reduces mycobacterial siderophores
Arnold, F. M., Weber, M. S., Gonda, I., Gallenito, M. J., Adenau, S., Egloff, P., … Seeger, M. A. (2020). The ABC exporter IrtAB imports and reduces mycobacterial siderophores. Nature, 580(7803), 413-417. https://doi.org/10.1038/s41586-020-2136-9
Structures in tetrahydrofolate methylation in desulfitobacterial glycine betaine metabolism at atomic resolution
Badmann, T., & Groll, M. (2020). Structures in tetrahydrofolate methylation in desulfitobacterial glycine betaine metabolism at atomic resolution. ChemBioChem, 21(6), 776-779. https://doi.org/10.1002/cbic.201900515
On-surface synthesis of nonmetal porphyrins
Baklanov, A., Garnica, M., Robert, A., Bocquet, M. L., Seufert, K., Küchle, J. T., … Auwärter, W. (2020). On-surface synthesis of nonmetal porphyrins. Journal of the American Chemical Society, 142(4), 1871-1881. https://doi.org/10.1021/jacs.9b10711
Mechanisms of regulation and diverse activities of tau-tubulin kinase (TTBK) isoforms
Bao, C., Bajrami, B., Marcotte, D. J., Chodaparambil, J. V., Kerns, H. M., Henderson, J., … Dillon, G. M. (2020). Mechanisms of regulation and diverse activities of tau-tubulin kinase (TTBK) isoforms. Cellular and Molecular Neurobiology. https://doi.org/10.1007/s10571-020-00875-6
 

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