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Identification of <em>Chlamydomonas</em> central core centriolar proteins reveals a role for human WDR90 in ciliogenesis
Hamel, V., Steib, E., Hamelin, R., Armand, F., Borgers, S., Flückiger, I., … Gönczy, P. (2017). Identification of Chlamydomonas central core centriolar proteins reveals a role for human WDR90 in ciliogenesis. Current Biology, 27(16), 2486-2498. https://doi.org/10.1016/j.cub.2017.07.011
Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex
Jiang, K., Rezabkova, L., Hua, S., Liu, Q., Capitani, G., Altelaar, A. F. M., … Akhmanova, A. (2017). Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex. Nature Cell Biology, 19(5), 480-492. https://doi.org/10.1038/ncb3511
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
Jost, M., Chen, Y., Gilbert, L. A., Horlbeck, M. A., Krenning, L., Menchon, G., … Weissman, J. S. (2017). Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent. Molecular Cell, 68(1), 210-223. https://doi.org/10.1016/j.molcel.2017.09.012
Short linear sequence motif LxxPTPh targets diverse proteins to growing microtubule ends
Kumar, A., Manatschal, C., Rai, A., Grigoriev, I., Steiner Degen, M., Jaussi, R., … Steinmetz, M. O. (2017). Short linear sequence motif LxxPTPh targets diverse proteins to growing microtubule ends. Structure, 25(6), 924-932. https://doi.org/10.1016/j.str.2017.04.010
Structural basis of microtubule stabilization by discodermolide
Prota, A. E., Bargsten, K., Redondo-Horcajo, M., Smith, A. B., Yang, C. P. H., McDaid, H. M., … Steinmetz, M. O. (2017). Structural basis of microtubule stabilization by discodermolide. ChemBioChem, 18(10), 905-909. https://doi.org/10.1002/cbic.201600696
Structural basis of katanin p60:p80 complex formation
Rezabkova, L., Jiang, K., Capitani, G., Prota, A. E., Akhmanova, A., Steinmetz, M. O., & Kammerer, R. A. (2017). Structural basis of katanin p60:p80 complex formation. Scientific Reports, 7, 14893 (8 pp.). https://doi.org/10.1038/s41598-017-14194-2
Quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulin
Sharma, A., Sáez-Calvo, G., Olieric, N., de Asís Balaguer, F., Barasoain, I., Lamberth, C., … Steinmetz, M. O. (2017). Quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulin. International Journal of Molecular Sciences, 18(7), 1336 (11 pp.). https://doi.org/10.3390/ijms18071336
Triazolopyrimidines are microtubule-stabilizing agents that bind the vinca inhibitor site of tubulin
Sáez-Calvo, G., Sharma, A., de Asís Balaguer, F., Barasoain, I., Rodríguez-Salarichs, J., Olieric, N., … Díaz, J. F. (2017). Triazolopyrimidines are microtubule-stabilizing agents that bind the vinca inhibitor site of tubulin. Cell Chemical Biology, 24(6), 737-750. https://doi.org/10.1016/j.chembiol.2017.05.016
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
Weinert, T., Olieric, N., Cheng, R., Brünle, S., James, D., Ozerov, D., … Standfuss, J. (2017). Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nature Communications, 8(1), 542 (11 pp.). https://doi.org/10.1038/s41467-017-00630-4
Kinesin-4 KIF21B is a potent microtubule pausing factor
van Riel, W. E., Rai, A., Bianchi, S., Katrukha, E. A., Liu, Q., Heck, A. J. R., … Akhmanova, A. (2017). Kinesin-4 KIF21B is a potent microtubule pausing factor. eLife, 6, e24746 (30 pp.). https://doi.org/10.7554/eLife.24746