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Structure-based discovery and rational design of microtubule-targeting agents
Steinmetz, M. O., & Prota, A. E. (2024). Structure-based discovery and rational design of microtubule-targeting agents. Current Opinion in Structural Biology, 87, 102845 (15 pp.). https://doi.org/10.1016/j.sbi.2024.102845
Mechanical forces and the 3D genome
Shivashankar, G. V. (2023). Mechanical forces and the 3D genome. Current Opinion in Structural Biology, 83, 102728 (7 pp.). https://doi.org/10.1016/j.sbi.2023.102728
Centriole length control
Sharma, A., Olieric, N., & Steinmetz, M. O. (2021). Centriole length control. Current Opinion in Structural Biology, 66, 89-95. https://doi.org/10.1016/j.sbi.2020.10.011
Structure and function of adenylyl cyclases, key enzymes in cellular signaling
Khannpnavar, B., Mehta, V., Qi, C., & Korkhov, V. (2020). Structure and function of adenylyl cyclases, key enzymes in cellular signaling. Current Opinion in Structural Biology, 63, 34-41. https://doi.org/10.1016/j.sbi.2020.03.003
Imaging of post-mortem human brain tissue using electron and X-ray microscopy
Lewis, A. J., Genoud, C., Pont, M., van de Berg, W. D. J., Frank, S., Stahlberg, H., … Al-Amoudi, A. (2019). Imaging of post-mortem human brain tissue using electron and X-ray microscopy. Current Opinion in Structural Biology, 58, 138-148. https://doi.org/10.1016/j.sbi.2019.06.003
Membrane protein dynamics studied by X-ray lasers - or why only time will tell
Standfuss, J. (2019). Membrane protein dynamics studied by X-ray lasers - or why only time will tell. Current Opinion in Structural Biology, 57, 63-71. https://doi.org/10.1016/j.sbi.2019.02.001
Active sites without restraints: high-resolution analysis of metal cofactors
Burger, E. M., Andrade, S. L. A., & Einsle, O. (2015). Active sites without restraints: high-resolution analysis of metal cofactors. Current Opinion in Structural Biology, 35, 32-40. https://doi.org/10.1016/j.sbi.2015.07.016
Membrane protein structural biology using X-ray free electron lasers
Neutze, R., Brändén, G., & Schertler, G. F. X. (2015). Membrane protein structural biology using X-ray free electron lasers. Current Opinion in Structural Biology, 33, 115-125. https://doi.org/10.1016/j.sbi.2015.08.006
Molecular mechanism of phosphorylation-dependent arrestin activation
Ostermaier, M. K., Schertler, G. F. X., & Standfuss, J. (2014). Molecular mechanism of phosphorylation-dependent arrestin activation. Current Opinion in Structural Biology, 29, 143-151. https://doi.org/10.1016/j.sbi.2014.07.006
Does the nucleosome break its own rules?
Davey, C. A. (2013). Does the nucleosome break its own rules? Current Opinion in Structural Biology, 23(2), 311-313. https://doi.org/10.1016/j.sbi.2013.01.011
Production of GPCR and GPCR complexes for structure determination
Maeda, S., & Schertler, G. F. X. (2013). Production of GPCR and GPCR complexes for structure determination. Current Opinion in Structural Biology, 23(3), 381-392. https://doi.org/10.1016/j.sbi.2013.04.006
Directly from the source: Endogenous preparations of molecular machines
Mesa, P., Deniaud, A., Montoya, G., & Schaffitzel, C. (2013). Directly from the source: Endogenous preparations of molecular machines. Current Opinion in Structural Biology, 23(3), 319-325. https://doi.org/10.1016/j.sbi.2013.01.005
Structural insights into agonist-induced activation of G-protein-coupled receptors
Deupi, X., & Standfuss, J. (2011). Structural insights into agonist-induced activation of G-protein-coupled receptors. Current Opinion in Structural Biology, 21(4), 541-551. https://doi.org/10.1016/j.sbi.2011.06.002
Viruses and sialic acids: rules of engagement
Neu, U., Bauer, J., & Stehle, T. (2011). Viruses and sialic acids: rules of engagement. Current Opinion in Structural Biology, 21(5), 610-618. https://doi.org/10.1016/j.sbi.2011.08.009
Membranes
Stroud, R. M., & Schertler, G. F. X. (2011). Membranes. Current Opinion in Structural Biology, 21(4), 495-496. https://doi.org/10.1016/j.sbi.2011.08.001
Nucleosome structural studies
Tan, S., & Davey, C. A. (2011). Nucleosome structural studies. Current Opinion in Structural Biology, 21(1), 128-136. https://doi.org/10.1016/j.sbi.2010.11.006
Interactions of the ribosome with mRNA and tRNA
Demeshkina, N., Jenner, L., Yusupova, G., & Yusupov, M. (2010). Interactions of the ribosome with mRNA and tRNA. Current Opinion in Structural Biology, 20(3), 325-332. https://doi.org/10.1016/j.sbi.2010.03.002
Coupling electron cryomicroscopy and X-ray crystallography to understand secondary active transport
Tsai, C. J., & Ziegler, C. (2010). Coupling electron cryomicroscopy and X-ray crystallography to understand secondary active transport. Current Opinion in Structural Biology, 20(4), 448-455. https://doi.org/10.1016/j.sbi.2010.06.005
A movie of the RNA polymerase nucleotide addition cycle
Brueckner, F., Ortiz, J., & Cramer, P. (2009). A movie of the RNA polymerase nucleotide addition cycle. Current Opinion in Structural Biology, 19(3), 294-299. https://doi.org/10.1016/j.sbi.2009.04.005
Proteins: how RNA polymerases work
Cramer, P., & Arnold, E. (2009). Proteins: how RNA polymerases work. Current Opinion in Structural Biology, 19(6), 680-682. https://doi.org/10.1016/j.sbi.2009.10.013