| Inductively coupled plasma mass spectrometry - a valid method for the characterization of metal conjugates in view of the development of radiopharmaceuticals
Wallimann, R. H., Schindler, P., Hensinger, H., Tschan, V. J., Busslinger, S. D., Kneuer, R., … Schibli, R. (2023). Inductively coupled plasma mass spectrometry - a valid method for the characterization of metal conjugates in view of the development of radiopharmaceuticals. Molecular Pharmaceutics, 20(4), 2150-2158. https://doi.org/10.1021/acs.molpharmaceut.2c01092 |
| Design and evaluation of novel albumin-binding folate radioconjugates: systematic approach of varying the linker entities
Benešová, M., Guzik, P., Deberle, L. M., Busslinger, S. D., Landolt, T., Schibli, R., & Müller, C. (2022). Design and evaluation of novel albumin-binding folate radioconjugates: systematic approach of varying the linker entities. Molecular Pharmaceutics, 19, 963-973. https://doi.org/10.1021/acs.molpharmaceut.1c00932 |
| Preclinical investigations to explore the difference between the diastereomers [<sup>177</sup>Lu]Lu-SibuDAB and [<sup>177</sup>Lu]Lu-RibuDAB toward prostate cancer therapy
Borgna, F., Deberle, L. M., Busslinger, S. D., Tschan, V. J., Walde, L. M., Becker, A. E., … Müller, C. (2022). Preclinical investigations to explore the difference between the diastereomers [177Lu]Lu-SibuDAB and [177Lu]Lu-RibuDAB toward prostate cancer therapy. Molecular Pharmaceutics, 19(7), 2105-2114. https://doi.org/10.1021/acs.molpharmaceut.1c00994 |
| Combined application of albumin-binding [<sup>177</sup>Lu]Lu-PSMA-ALB-56 and fast-cleared PSMA inhibitors: optimization of the pharmacokinetics
Borgna, F., Deberle, L. M., Cohrs, S., Schibli, R., & Müller, C. (2020). Combined application of albumin-binding [177Lu]Lu-PSMA-ALB-56 and fast-cleared PSMA inhibitors: optimization of the pharmacokinetics. Molecular Pharmaceutics, 17(6), 2044-2053. https://doi.org/10.1021/acs.molpharmaceut.0c00199 |
| Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting
Kaeppeli, S. A. M., Jodal, A., Gotthardt, M., Schibli, R., & Behe, M. (2019). Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting. Molecular Pharmaceutics, 16(9), 3760-3769. https://doi.org/10.1021/acs.molpharmaceut.9b00271 |
| Albumin-binding PSMA ligands: optimization of the tissue distribution profile
Benešová, M., Umbricht, C. A., Schibli, R., & Müller, C. (2018). Albumin-binding PSMA ligands: optimization of the tissue distribution profile. Molecular Pharmaceutics, 15(3), 934-946. https://doi.org/10.1021/acs.molpharmaceut.7b00877 |
| Enhanced specific activity by multichelation of exendin-3 leads to improved image quality and <em>In Vivo </em>Beta cell imaging
Joosten, L., Brom, M., Peeters, H., Heskamp, S., Béhé, M., Boerman, O., & Gotthardt, M. (2018). Enhanced specific activity by multichelation of exendin-3 leads to improved image quality and In Vivo Beta cell imaging. Molecular Pharmaceutics, 15(2), 486-494. https://doi.org/10.1021/acs.molpharmaceut.7b00853 |
| In vivo labeling of plasma proteins for imaging of enhanced vascular permeability in the lungs
Schniering, J., Borgna, F., Siwowska, K., Benešová, M., Cohrs, S., Hasler, R., … Müller, C. (2018). In vivo labeling of plasma proteins for imaging of enhanced vascular permeability in the lungs. Molecular Pharmaceutics, 15(11), 4995-5004. https://doi.org/10.1021/acs.molpharmaceut.8b00606 |
| Design and preclinical evaluation of an albumin-binding PSMA ligand for <sup>64</sup>Cu-based PET imaging
Umbricht, C. A., Benešová, M., Hasler, R., Schibli, R., van der Meulen, N. P., & Müller, C. (2018). Design and preclinical evaluation of an albumin-binding PSMA ligand for 64Cu-based PET imaging. Molecular Pharmaceutics, 15(12), 5556-5564. https://doi.org/10.1021/acs.molpharmaceut.8b00712 |
| Preclinical development of novel PSMA-targeting radioligands: modulation of albumin-binding properties to improve prostate cancer therapy
Umbricht, C. A., Benešová, M., Schibli, R., & Müller, C. (2018). Preclinical development of novel PSMA-targeting radioligands: modulation of albumin-binding properties to improve prostate cancer therapy. Molecular Pharmaceutics, 15(6), 2297-2306. https://doi.org/10.1021/acs.molpharmaceut.8b00152 |
| Radiolabeled <sup>111</sup>In-FGF-2 is suitable for <em>In Vitro</em>/<em>Ex Vivo </em>evaluations and <em>In Vivo </em>imaging
Moscaroli, A., Jones, G., Lühmann, T., Meinel, L., Wälti, S., Blanc, A., … Béhé, M. (2017). Radiolabeled 111In-FGF-2 is suitable for In Vitro/Ex Vivo evaluations and In Vivo imaging. Molecular Pharmaceutics, 14(3), 639-648. https://doi.org/10.1021/acs.molpharmaceut.6b00913 |
| Preclinical comparison of albumin-binding radiofolates: impact of linker entities on the in vitro and in vivo properties
Siwowska, K., Haller, S., Bortoli, F., Benešová, M., Groehn, V., Bernhardt, P., … Müller, C. (2017). Preclinical comparison of albumin-binding radiofolates: impact of linker entities on the in vitro and in vivo properties. Molecular Pharmaceutics, 14(2), 523-532. https://doi.org/10.1021/acs.molpharmaceut.6b01010 |
| <sup>64</sup>Cu- and <sup>68</sup>Ga-based PET imaging of folate receptor-positive tumors: development and evaluation of an albumin-binding NODAGA−folate
Farkas, R., Siwowska, K., Ametamey, S. M., Schibli, R., van der Meulen, N. P., & Müller, C. (2016). 64Cu- and 68Ga-based PET imaging of folate receptor-positive tumors: development and evaluation of an albumin-binding NODAGA−folate. Molecular Pharmaceutics, 13(6), 1979-1987. https://doi.org/10.1021/acs.molpharmaceut.6b00143 |
| Nanostructured drugs embedded into a polymeric matrix: vinpocetine/PVP hybrids investigated by Debye function analysis
Hasa, D., Giacobbe, C., Perissutti, B., Voinovich, D., Grassi, M., Cervellino, A., … Guagliardi, A. (2016). Nanostructured drugs embedded into a polymeric matrix: vinpocetine/PVP hybrids investigated by Debye function analysis. Molecular Pharmaceutics, 13(9), 3034-3042. https://doi.org/10.1021/acs.molpharmaceut.6b00124 |
| Site-specific conjugation of monomethyl auristatin E to Anti-CD30 antibodies improves their pharmacokinetics and therapeutic index in rodent models
Lhospice, F., Brégeon, D., Belmant, C., Dennler, P., Chiotellis, A., Fischer, E., … Romagné, F. (2015). Site-specific conjugation of monomethyl auristatin E to Anti-CD30 antibodies improves their pharmacokinetics and therapeutic index in rodent models. Molecular Pharmaceutics, 12(6), 1863-1871. https://doi.org/10.1021/mp500666j |
| Folate receptor-targeted multimodality imaging of ovarian cancer in a novel syngeneic mouse model
Ocak, M., Gillman, A. G., Bresee, J., Zhang, L., Vlad, A. M., Müller, C., … Gach, H. M. (2014). Folate receptor-targeted multimodality imaging of ovarian cancer in a novel syngeneic mouse model. Molecular Pharmaceutics, 12(2), 542-553. https://doi.org/10.1021/mp500628g |
| [<sup>3</sup>H]metyrapol and 4-[<sup>131</sup>I]iodometomidate label overlapping, but not identical, binding sites on rat adrenal membranes
Berger, M. L., Hammerschmidt, F., Qian, R., Hahner, S., Schirbel, A., Stichelberger, M., … Zolle, I. M. (2013). [3H]metyrapol and 4-[131I]iodometomidate label overlapping, but not identical, binding sites on rat adrenal membranes. Molecular Pharmaceutics, 10(3), 1119-1130. https://doi.org/10.1021/mp3006227 |
| In vitro and in vivo evaluation of an innocuous drug cocktail to improve the quality of folic acid targeted nuclear imaging in preclinical research
Müller, C., Reber, J., Schlup, C., Leamon, C. P., & Schibli, R. (2013). In vitro and in vivo evaluation of an innocuous drug cocktail to improve the quality of folic acid targeted nuclear imaging in preclinical research. Molecular Pharmaceutics, 10(3), 967-974. https://doi.org/10.1021/mp300428p |
| Radioiodinated folic acid conjugates: evaluation of a valuable concept to improve tumor-to-background contrast
Reber, J., Struthers, H., Betzel, T., Hohn, A., Schibli, R., & Müller, C. (2012). Radioiodinated folic acid conjugates: evaluation of a valuable concept to improve tumor-to-background contrast. Molecular Pharmaceutics, 9(5), 1213-1221. https://doi.org/10.1021/mp200511t |
| Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of <sup>99m</sup>Tc-EC20 in xenografted and syngeneic tumor-bearing mice
Müller, C., Reddy, J. A., Leamon, C. P., & Schibli, R. (2010). Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of 99mTc-EC20 in xenografted and syngeneic tumor-bearing mice. Molecular Pharmaceutics, 7(2), 597-604. https://doi.org/10.1021/mp900296k |
