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Prostate-specific membrane antigen–targeted therapies for prostate cancer: towards improving therapeutic outcomes
Corpetti, M., Müller, C., Beltran, H., de Bono, J., & Theurillat, J. P. (2024). Prostate-specific membrane antigen–targeted therapies for prostate cancer: towards improving therapeutic outcomes. European Urology, 85(3), 193-204. https://doi.org/10.1016/j.eururo.2023.11.018
Design and preclinical evaluation of a novel prostate-specific membrane antigen radioligand modified with a transthyretin binder
Vaccarin, C., Mapanao, A. K., Deberle, L. M., Becker, A. E., Borgna, F., Marzaro, G., … Müller, C. (2024). Design and preclinical evaluation of a novel prostate-specific membrane antigen radioligand modified with a transthyretin binder. Cancers, 16(7), 1262 (13 pp.). https://doi.org/10.3390/cancers16071262
Albumin-binding and conventional PSMA ligands in combination with <sup>161</sup>Tb: biodistribution, dosimetry, and preclinical therapy
Tschan, V. J., Busslinger, S. D., Bernhardt, P., Grundler, P. V., Zeevaart, J. R., Köster, U., … Müller, C. (2023). Albumin-binding and conventional PSMA ligands in combination with 161Tb: biodistribution, dosimetry, and preclinical therapy. Journal of Nuclear Medicine, 64(10), 1625-1631. https://doi.org/10.2967/jnumed.123.265524
Preclinical investigations to explore the difference between the diastereomers [<sup>177</sup>Lu]Lu-SibuDAB and [<sup>177</sup>Lu]Lu-RibuDAB toward prostate cancer therapy
Borgna, F., Deberle, L. M., Busslinger, S. D., Tschan, V. J., Walde, L. M., Becker, A. E., … Müller, C. (2022). Preclinical investigations to explore the difference between the diastereomers [177Lu]Lu-SibuDAB and [177Lu]Lu-RibuDAB toward prostate cancer therapy. Molecular Pharmaceutics, 19(7), 2105-2114. https://doi.org/10.1021/acs.molpharmaceut.1c00994
[<sup>225</sup>Ac]Ac-SibuDAB for targeted alpha therapy of prostate cancer: preclinical evaluation and comparison with [<sup>225</sup>Ac]Ac-PSMA-617
Busslinger, S. D., Tschan, V. J., Richard, O. K., Talip, Z., Schibli, R., & Müller, C. (2022). [225Ac]Ac-SibuDAB for targeted alpha therapy of prostate cancer: preclinical evaluation and comparison with [225Ac]Ac-PSMA-617. Cancers, 14(22), 5651 (16 pp.). https://doi.org/10.3390/cancers14225651
Preclinical investigations using [<sup>177</sup>Lu]Lu-Ibu-DAB-PSMA toward its clinical translation for radioligand therapy of prostate cancer
Tschan, V. J., Borgna, F., Busslinger, S. D., Stirn, M., Monné Rodriguez, J. M., Bernhardt, P., … Müller, C. (2022). Preclinical investigations using [177Lu]Lu-Ibu-DAB-PSMA toward its clinical translation for radioligand therapy of prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging, 49, 3639-3650. https://doi.org/10.1007/s00259-022-05837-2
Dosimetric analysis of the short-ranged particle emitter <sup>161</sup>Tb for radionuclide therapy of metastatic prostate cancer
Bernhardt, P., Svensson, J., Hemmingsson, J., van der Meulen, N. P., Zeevaart, J. R., Konijnenberg, M. W., … Kindblom, J. (2021). Dosimetric analysis of the short-ranged particle emitter 161Tb for radionuclide therapy of metastatic prostate cancer. Cancers, 13(9), 2011 (13 pp.). https://doi.org/10.3390/cancers13092011
Biodistribution and dosimetry of a single dose of albumin-binding ligand [<sup>177</sup>Lu]Lu-PSMA-ALB-56 in patients with mCRPC
Kramer, V., Fernández, R., Lehnert, W., Jiménez-Franco, L. D., Soza-Ried, C., Eppard, E., … Müller, C. (2021). Biodistribution and dosimetry of a single dose of albumin-binding ligand [177Lu]Lu-PSMA-ALB-56 in patients with mCRPC. European Journal of Nuclear Medicine and Molecular Imaging, 48, 893-903. https://doi.org/10.1007/s00259-020-05022-3
Combined application of albumin-binding [&lt;sup&gt;177&lt;/sup&gt;Lu]Lu-PSMA-ALB-56 and fast-cleared PSMA inhibitors: optimization of the pharmacokinetics
Borgna, F., Deberle, L. M., Cohrs, S., Schibli, R., & Müller, C. (2020). Combined application of albumin-binding [177Lu]Lu-PSMA-ALB-56 and fast-cleared PSMA inhibitors: optimization of the pharmacokinetics. Molecular Pharmaceutics, 17(6), 2044-2053. https://doi.org/10.1021/acs.molpharmaceut.0c00199
Albumin-binding PSMA radioligands: impact of minimal structural changes on the tissue distribution profile
Deberle, L. M., Tschan, V. J., Borgna, F., Sozzi-Guo, F., Bernhardt, P., Schibli, R., & Müller, C. (2020). Albumin-binding PSMA radioligands: impact of minimal structural changes on the tissue distribution profile. Molecules, 25(11), 2542 (16 pp.). https://doi.org/10.3390/molecules25112542
Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity
Deberle, L. M., Benešová, M., Umbricht, C. A., Borgna, F., Büchler, M., Zhernosekov, K., … Müller, C. (2020). Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity. Theranostics, 10(4), 1678-1693. https://doi.org/10.7150/thno.40482
Concentration‐dependent effects of dutasteride on prostate‐specific membrane antigen (PSMA) expression and uptake of &lt;sup&gt;177&lt;/sup&gt;Lu‐PSMA‐617 in LNCaP cells
Kranzbühler, B., Salemi, S., Umbricht, C. A., Deberle, L. M., Müller, C., Burger, I. A., … Eberli, D. (2019). Concentration‐dependent effects of dutasteride on prostate‐specific membrane antigen (PSMA) expression and uptake of 177Lu‐PSMA‐617 in LNCaP cells. Prostate, 79(12), 1477-1483. https://doi.org/10.1002/pros.23868
Preclinical investigations and first-in-human application of &lt;sup&gt;152&lt;/sup&gt;Tb-PSMA-617 for PET/CT imaging of prostate cancer
Müller, C., Singh, A., Umbricht, C. A., Kulkarni, H. R., Johnston, K., Benešová, M., … Baum, R. P. (2019). Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer. EJNMMI Research, 9(1), 68 (10 pp.). https://doi.org/10.1186/s13550-019-0538-1
Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer
Müller, C., Umbricht, C. A., Gracheva, N., Tschan, V. J., Pellegrini, G., Bernhardt, P., … van der Meulen, N. P. (2019). Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging, 46(9), 1919-1930. https://doi.org/10.1007/s00259-019-04345-0
Targeted &lt;sup&gt;64&lt;/sup&gt;Cu-labeled gold nanoparticles for dual imaging with positron emission tomography and optical imaging
Pretze, M., van der Meulen, N.  P., Wängler, C., Schibli, R., & Wängler, B. (2019). Targeted 64Cu-labeled gold nanoparticles for dual imaging with positron emission tomography and optical imaging. Journal of Labelled Compounds and Radiopharmaceuticals, 62(8), 471-482. https://doi.org/10.1002/jlcr.3736
First clinico-pathological evidence of a non PSMA-related uptake mechanism for &lt;sup&gt;68&lt;/sup&gt;Ga-PSMA-11 in salivary glands
Rupp, N. J., Umbricht, C. A., Pizzuto, D. A., Lenggenhager, D., Töpfer, A., Müller, J., … Burger, I. A. (2019). First clinico-pathological evidence of a non PSMA-related uptake mechanism for 68Ga-PSMA-11 in salivary glands. Journal of Nuclear Medicine, 60(9), 1270-1276. https://doi.org/10.2967/jnumed.118.222307
Albumin-binding PSMA ligands: optimization of the tissue distribution profile
Benešová, M., Umbricht, C. A., Schibli, R., & Müller, C. (2018). Albumin-binding PSMA ligands: optimization of the tissue distribution profile. Molecular Pharmaceutics, 15(3), 934-946. https://doi.org/10.1021/acs.molpharmaceut.7b00877
Structural analysis of small-molecule binding to the BAZ2A and BAZ2B Bromodomains
Dalle Vedove, A., Spiliotopoulos, D., D'Agostino, V. G., Marchand, J. R., Unzue, A., Nevado, C., … Caflisch, A. (2018). Structural analysis of small-molecule binding to the BAZ2A and BAZ2B Bromodomains. ChemMedChem, 13(14), 1479-1487. https://doi.org/10.1002/cmdc.201800234
Pharmacological upregulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells
Kranzbühler, B., Salemi, S., Umbricht, C. A., Müller, C., Burger, I. A., Sulser, T., & Eberli, D. (2018). Pharmacological upregulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells. Prostate, 78(10), 758-765. https://doi.org/10.1002/pros.23522
Design and preclinical evaluation of an albumin-binding PSMA ligand for &lt;sup&gt;64&lt;/sup&gt;Cu-based PET imaging
Umbricht, C. A., Benešová, M., Hasler, R., Schibli, R., van der Meulen, N. P., & Müller, C. (2018). Design and preclinical evaluation of an albumin-binding PSMA ligand for 64Cu-based PET imaging. Molecular Pharmaceutics, 15(12), 5556-5564. https://doi.org/10.1021/acs.molpharmaceut.8b00712