Global changes pose both risks and opportunities to agriculture and forestry, and biological forecasts can inform future management strategies. Here, we investigate potential land-use opportunities arising from climate change for these sectors in Europe, and risks associated with the introduction and establishment of novel insect pests. Adopting a metaweb approach including all interaction links between 126 crops and forest tree species and 89 black-listed insect pest species, we show that the metawebs shift toward increased numbers of links and overlap of suitable area under climate change. Decomposing the metaweb across regions shows large saturation in southern Europe, while many novel interactions are expected for northern Europe. In light of the rising consumer awareness about human health and environmental impacts of food and wood production, the challenge will be to effectively exploit new opportunities to create diverse local agriculture and forestry while controlling pest species and reducing risks from pesticide use.