Climate model ensembles serve as an input to all impact studies that use sector-specific models (e.g., hydrological, ecological, crop models, fire hazard) at regional or local scales. These models require regionally scaled climate information to simulate the potential environmental and socio-economic sectoral impacts of climate change. Such simulations are based on comprehensive multi-member climate ensembles derived from the bias-adjusted and downscaled global and regional climate models. Due to limited computational resources, users of climate scenarios often can only include a small number of the ensemble members in their calculations, and therefore they often select them at random. A pre-selection of meaningful, consistent and case-specific members is therefore desired by the climate data users. In this work, we aim to fill this gap and present a novel user-tailored procedure for sub-selecting ensemble members for a variety of applications. Our method is based on the ranking of the climate change signal (CCS) calculated for a set of climate indices (e.g., mean temperature or number of hot days). Based on the CCS strength, three ensemble members representing the strongest, weakest, and median CCS are selected for each application. We also demonstrate the robustness of our approach in a specific hydrological impact model framework. Providing a systematic procedure not only assists impact modelers in selecting appropriate members, but also improves the consistency and comparability of different impact studies.