Landscape genetics is now ten years old. It has stimulated research into the effect of landscapes on evolutionary processes. This review describes the main topics that have contributed most significantly to the progress of landscape genetics, such as conceptual and methodological developments in spatial and temporal patterns of gene flow, seascape genetics, and landscape genomics. We then suggest perspectives for the future, investigating what the field will contribute to the assessment of global change and conservation in general and to the management of tropical and urban areas in particular. To address these urgent topics, future work in landscape genetics should focus on a better integration of neutral and adaptive genetic variation and their interplay with species distribution and the environment.